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Showing 1 to 1 of 1 for “"HLA class II polymorphism"”.
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Biochemical and Immunological Mechanisms Underlying Differential Interaction of Superantigens with Host Immunogenetic Factors in Streptococcal Sepsis
… (Strep SAgs). SAgs interact simultaneously with HLA class II molecules on antigen presenting cells (APC) and with the T cell receptor beta chain variable elements (TCR V) and cause excessive stimulation of both cell types and massive release of inflammatory mediators. </p> <p>The Strep SAgs …