Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 270 for “"HL"”.
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Genetic analysis of the hl locus in maize
… of the donor parent DNA segment retained in Oh43 hlhl and H95 hlhl was estimated to be 30 and 40 cM, respectively. The information provided by the genetic analysis of the h1 locus may be of value for marker-assisted backcross breeding and eventually, for gene tagging and cloning. Zeins were …
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Lysosomal Enzymes in Undifferentiated and Differentiated HL-60 Cells
<p>The human promyelocytic leukemia cell line HL-60 has been studied extensively since the time of it's discovery and has been proven to be a valuable tool for the study of the differentiation process. The capacity of the HL-60 cell line to differentiate to macrophage-like cells, which may be …
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Digital image analysis of HL-60 proliferation and granulocytic differentiation.
… and granulocytic differentiation of HL-60 leukemia cells which were induced to differentiate by retinoic acid (RA). HL-60 cells were synchronized by density arrest (DA), double thymidine block (TB), or flow cytometric sort (FCM). Following release from the 3 modes of synchrony, …
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Nesfatin-1 Regulation of Cardiovascular Functions in Zebrafish and HL-1 Cardiomyocytes
… was detected in the cytoplasm of mouse HL-1 cardiomyocytes. High glucose increased NUCB2 mRNA expression in HL-1 cells. Genes involved in apoptosis, including Akt1, Caspases 1, 2, 3, and TNF were upregulated in the presence of 10 nM nesfatin-1. We also observed that NUCB2 mRNA expression …
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Collagen-Glycosaminoglycan Scaffold Systems to Assess HL-1 Cardiomyocyte Beating and Alignment
… examine the alignment and beating potential of HL-1 cardiomyoctyes in a 3D environment. Collagen-glycosaminoglycan scaffolds have been used extensively to probe the behavior of mature cells in vitro, but have not yet been designed for cardiac applications. In order to recapitulate key properties …
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Investigation of Neutrophil-Like HL-60 Cell Migration in a 3D Collagen Matrix
… a collagen gel that contained neutrophil-like (dHL-60) cells. Our experimental setup and computational analysis allowed us to study the cell migration indicators such as percentage and velocity of motile cells in a 3D environment. Evaluating these cell migration features showed 10 nM …
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The effect of P-selectin pattern width on HL-60 cell rolling behavior
… band patterns on the rolling behavior of HL- 60 myeloid cells along edges of the band patterns was studied. The P-selectin and polyethylene glycol (PEG) pattern was produced via microcontact printing using a polydimethylsiloxane (PDMS) stamp. HL-60 cells were flowed across the pattern …
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Development of Small-Pitch, Thin 3D Sensors for Pixel Detector Upgrades at HL-LHC
… at LHC. However, the future High-Luminosity LHC (HL-LHC) upgrades, aimed to be operational by 2024, impose a complete swap of current 3D detectors with more radiation hard sensor design, able to withstand very large particle fluences up to 2×1016 cm-2 1-MeV equivalent neutrons. The extreme …
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Quantitative Image Analysis in the Study of Neutrophil and Neutrophil-Like HL-60 Chemotaxis
Neutrophils are fast-moving first responders of the innate immune system. External chemoattractant signals result in neutrophil polarization: the neutrophil forms a leading edge (front) which constantly protrudes and retracts actin-rich pseudopods, and a contractile myosin-enriched trailing edge …
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Higgs pair production in [beta][beta][tau][tau] final states at the HL-LHC
A measurement of standard model Higgs pair production in [beta][beta][tau][tau] final states at the High Luminosity LHC is investigated. Higgs pair production can be used to measure the Higgs trilinear coupling constant, which uniquely determines the shape of the Higgs potential. The doubly …
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Development of enhanced double-sided 3D radiation sensors for pixel detector upgrades at HL-LHC
The upgrades of High Energy Physics (HEP) experiments at the Large Hadron Collider (LHC) will call for new radiation hard technologies to be applied in the next generations of tracking devices that will be required to withstand extremely high radiation doses. In this sense, one of the most …
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Developing second language confidence: The effect of videoconferencing on L2 and HL learners of Spanish
… on the development of L2C in L2 and HL learners of Spanish. The research questions that guided this study were: (1) Does interlocutor type (i.e., a peer on Zoom or a native speaker on Talk Abroad) play a role in the development of L2C in L2 and HL learners? Also, do these results vary …
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Learning opportunities and outcomes of L2-L2 and L2-HL learner interaction during a collaborative writing task
… question of what happens when heritage language (HL) learners are involved. This dissertation examines not only the connection between learner-learner interaction and language learning, but also whether learner linguistic background (L2, HL) plays a differential role in terms of both learning …
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Calcium Influx via the T-Type Calcium Channel Plays a Permissive Role in Proliferation of Mouse Embryonic Hl-1 Cells
… cell types. An atrial myocyte cell line (HL-1) that selectively expresses T-type calcium current was employed to show that inhibiting calcium influx through the T-type calcium channel inhibits cellular proliferation. Drug dosage studies demonstrate that the T-type calcium channel …
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Sphingosine-1-Phosphate and Fingolimod (FTY720) Regulate ICl,swell In HL-1 Cardiac Myocytes via Intracellular Binding And Mitochondrial ROS Production
<p>Swelling-activated Cl− current (ICl,swell) is an outwardly-rectifying current that plays an important role in cardiac electrical activity, cellular volume regulation, apoptosis, and acts as a potential effector of mechanoelectrical feedback. Persistent activation of ICl,swell has been observed …
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Building the Future: HL-LHC ATLAS Upgrades and Event-Topology-Based Principles to Search for New Physics with Missing Transverse Momentum
… Collider (LHC) upgrade to the High-Luminosity (HL) LHC imposes significant challenges to the detector hardware and the need for novel analysis strategies to extend the search for new physics. This dissertation presents upgrade projects in both frontiers. In regards to the development of the …
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