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Showing 1 to 2 of 2 for “"HIV-1 entry inhibition"”.
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The HIV-1 entry inhibition capabilities of Isoflavones
The availability of treatment for HIV infection has resulted in a drastic increase in the life expectancy of infected individuals. However, the current therapeutics fall short in many areas. A considerable 60% of treated individuals will show minor cognitive disorders due to infection, immune …
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Single Molecule Ligand Binding Studies on CCR5 by Fluorescence Cross-Correlation Spectroscopy
… receptor 5 (CCR5) is the major co-receptor for HIV-1. CCR5 binds to the viral glycoprotein gp120 allowing HIV particles to infect T cells. Currently, maraviroc is the only Food and Drug Administration (FDA) approved entry inhibitor for HIV-1 but resistance to maraviroc has been reported …