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Showing 1 to 1 of 1 for “"HIV-1 -- drug effects"”.
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Development of Catalytic RNAs as Potential Anti-HIV-1 Agents
… activity (ribozymes) targeted to the genome of HIV-1 were developed and demonstrated to mediate site-specific cleavage of the HIV-1 RNA in vitro and to inhibit viral proliferation intracellularly. Two classes of ribozymes that incorporate a "hammerhead" catalytic center were utilized, eotide …