Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"HIV latency"”.
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Regulation of HIV latency dynamics in monocytes and monocyte-derived macrophages
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
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The impact of heptose phosphates on HIV latency and human immune responses
Use of HIV-specific antiretroviral therapeutic agents (ARTs) achieves total control of viremia and prevents progression of HIV to AIDS, but they are not a cure. Shock-and-kill therapy aims to use HIV latency reversal agents to promote clearance of HIV infected CD4 T-cells that make up the HIV …
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Methods for inferring dynamical systems from biological data with applications to HIV latency and genetic drivers of aging
… and inferring the processes allowing latent HIV infection to persist and evade a cure with existing treatments.
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Development And Validation Of Novel Transmitted/founder Shivs For Hiv-1 Persistence And Cure Research
A robust simian-human immunodeficiency virus (SHIV)-rhesus macaque (RM) model of HIV latency and cure is needed. Our group has generated >20 SHIVs encoding various HIV-1 Envs of interest, including transmitted/founder (TF) Envs. TF SHIVs encode a substitution at Env residue 375 that confers …
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Role of delay differential equations in modelling low level HIV viral load
Over the past 30 years, HIV has infected over 60 million people, with almost half succumbing to AIDS-related illnesses.While antiretroviral therapy, used to significantly reduce within-host HIV replication, was available within 10 years of the discovery of HIV/AIDS, it is only within the last 10 …
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HETEROGENEITY OF LATENCY ESTABLISHMENT IN DIFFERENT HUMAN CD4+ T CELL SUBSETS STIMULATED WITH INTERLEUKIN-15
The Human Immunodeficiency Virus (HIV) integrates its genome into the host DNA and persists for the lifetime of the infected cell. Even in the presence of an efficacious Highly Active Anti-Retroviral Therapy (HAART) treatment, a pool of latently infected cells persists and reactivates to produce …
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THE ROLE OF CD4+ T MEMORY SUBSETS IN HIV INFECTION: IMMUNE RESPONSE IN PEOPLE WITH HIV AND LATENCY ESTABLISHMENT
… In the context of human immunodeficiency virus (HIV), CD4+ TSCM, serve as target of infection as well as reservoir, sustaining long-lived, self-renewing pools of latently infected cells despite antiretroviral therapy (ART). Thus, TSCM are central to both protective immunity and the persistence of …