Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"HIV infectivity"”.
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Association Among CCR5 Genotypes, CCR5 Expression, And In Vitro HIV Infection
… T lymphocytes. CCR5 is a major coreceptor for HIV to bind to the T cell prior to fusion. Individuals have various frequencies of these polymorphisms, which influence their susceptible to HIV infection and disease progression. This thesis is focused on determining the association between these …
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Antiretroviral therapy(ART) and sexual behaviour among people living with HIV: A case study of Lusaka
Background: With thousands of the HIV infected Zambian population on ART, there are worries that people on ART may be engaging in high risk sexual behaviours thereby nullifying the impact of current HIV prevention efforts.Objectives: This study therefore investigated sexual behaviours among people …
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Antiretroviral therapy(ART) and sexual behaviour among people living with HIV: A case study of Lusaka
Background: With thousands of the HIV infected Zambian population on ART, there are worries that people on ART may be engaging in high risk sexual behaviours thereby nullifying the impact of current HIV prevention efforts.Objectives: This study therefore investigated sexual behaviours among people …
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Characterisation of the HIV inhibitory activity of vaginal lactobacilli isolates from young South African women at high risk of HIV acquisition
… the acquisition of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs) in South African women. However, the microbial causes and the immunomodulatory effects of BV are not yet fully understood, and effective treatment strategies do not exist. BV is associated with …
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Intracellular Traits of Chimeric tRNAlys3-ribozymes and their Inhibition of HIV
<p>Host tRNALYs3is the primer recruited by HIV-1 for initiating reverse transcription. When ribozymes targeted upstream of the primer binding site of the HIV-1 genome are tethered to the 3' end of the tRNALYs3, it is expected that the tRNA will carry the ribozymes into the virions. We made …
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Investigate the effect of Bacterial Vaginosis-associated bacteria on the efficacy of Anti-HIV therapy
… with human immunodeficiency virus type 1 (HIV-1) remains one of the leading causes of death worldwide with young women in sub-Saharan Africa the most affected. Although pre-exposure prophylaxis (PrEP) with antiretroviral (ARV) drugs such as tenofovir (TFV) and emtricitabine have been shown …
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Investigate the effect of Bacterial Vaginosis-associated bacteria on the efficacy of Anti-HIV therapy
… with human immunodeficiency virus type 1 (HIV-1) remains one of the leading causes of death worldwide with young women in sub-Saharan Africa the most affected. Although pre-exposure prophylaxis (PrEP) with antiretroviral (ARV) drugs such as tenofovir (TFV) and emtricitabine have been shown …
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Effect of HIV infection and pregnancy on parameters of vaginal immunity
… Our study addresses the role of pregnancy and HIV infection on concentrations of cytokines in genital tract fluid that play a role in HIV sexual transmission. We focused on two pathways: The NF-KB inflammation pathway that has been implicated in susceptibility to HIV infection, and two …