Global ETD Search
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Showing 1 to 2 of 2 for “"HIV capsids"”.
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Differential modulation of HIV-1 capsid uncoating kinetics revealed by a novel single-particle uncoating assay
The HIV-1 capsid has been recognised as an attractive antiviral target due to its central role during infection. It acts as a shield to protect the viral genome, facilitates reverse transcription, engages with the nuclear pore complex, and directs integration site targeting. To achieve all of these …
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Statistical thermodynamics of virus assembly
… affects the structure of in vivo assembled HIV-1 capsid is studied. We show that conical and cylindrical capsids have similar energy at high surface tension of the viral membrane, which leads to the various shapes of HIV-1 capsids. Secondly, the problem of RNA genome packaging inside …