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Showing 1 to 1 of 1 for “"HIV/AIDS, myeloid cells, microglia, epigenetic suppression, BRD4 modulator, CNS"”.

  1. Modulation of Host BRD4 to Repress HIV Replication in Myeloid Cells: Major HIV Reservoirs in Central Nervous System

    Brain-resident microglia and myeloid cells (perivascular macrophages) are important HIV reservoirs in vivo, especially in central nerve system (CNS). Despite anti-retroviral therapy (ART), low-level persistent HIV replication in these reservoirs remains detectable, which contributes to …

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