Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 3531 for “"HIV"”.
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Biomarker identification in HIV and non-HIV related lymphomas
… in older populations as well as in younger HIV infected patients. The current treatment options for DLBCL are effective for most patients yet the relapse rate is high. While many biomarkers for DLBCL exist, they are not in clinical use due to low sensitivity and specificity. In addition, …
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HIV prevention communication in families affected by HIV/AIDS
… resource for educating children about HIV prevention. Parents and other family members can play a critical role in prevention efforts by using effective parenting practices, communicating their values and expectations, and modeling strategies that reduce the risk of acquiring HIV. …
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HIV-1 evolution, disease progression and molecular epidemiology of HIV-1 single and HIV-1 and HIV-2 dual-infected individuals in Guinea-Bissau
… related human lentiviruses known today, HIV-1 (which is pandemic) and HIV-2 (which mainly is confined to West Africa), are the causative agents of AIDS. Progressive immune dysfunction and AIDS develop in most cases of untreated HIV-1 infection, but only in approximately 25-30% of HIV-2 …
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HIV in the heartland: negotiating disclosure, stigma, & the HIV community
… continues to affect the American population and HIV/AIDS remains a social problem. Living with HIV affects every aspect of an individual’s life. It involves a personal negotiation at the onset of diagnosis, a social negotiation when one decides to disclose to others, and finally, a communal …
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HIV and penetrating abdominal trauma: does HIV influence the outcome?
Background: Human immunodeficiency virus (HIV) infection and trauma are significant contributors to the burden of disease in South Africa. There is an increase in prevalence of HIV sero-positivity in trauma patients. However, there are conflicting reports about the influence of HIV in outcomes …
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Understanding Mediators of the Relationship Between HIV-Related Stigma and Medication Adherence Among People Living with HIV (HIV)
… accumulated research demonstrates that HIV-related stigma is associated with medication adherence difficulties for PLWH, this literature is limited by inconsistencies in the conceptualization and assessment of both stigma and adherence. Additionally, few empirical research studies …
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Mechanisms of HIV-Nef Induced Endothelial Cell Stress: Implications of HIV-Nef Protein Persistence in Aviremic HIV Patients
HIV-associated cardio-pulmonary vascular pathologies such as coronary artery disease, pulmonary hypertension and emphysema remain a major issue in the HIVinfected population even in the era of antiretroviral therapy (ART). The continued production of HIV encoded pro-apoptotic protein, such as Nef …
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Radiological differences between HIV-positive and HIV-negative children with cholesteatoma
Introduction: HIV-positive children are possibly more prone to developing cholesteatoma. Chronic inflammation of the middle ear cleft may be more common in patients with HIV and this may predispose HIV-positive children to developing cholesteatoma. There are no studies that describe the …
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Genome scale identification of HIV Dependency factors across multiple HIV-1 strains
In this thesis, I developed a method called HIV-CRISPR screening at genome-wide scale, and then at a smaller, targeted scale, to uncover novel genes that may act as HIV-1 dependency factors. By using a screening technique which assesses enrichment or depletion of guide based on HIV-1 release from …
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Νέες θεραπευτικές παρεμβάσεις στην HIV λοίμωξη / New therapeutic interventions in HIV infection
Η HIV λοίμωξη (Ιός Ανθρώπινης Ανοσοανεπάρκειας) παραμένει μια από τις πιο σοβαρές παγκόσμιες προκλήσεις στον τομέα της Δημόσιας Υγείας. Η παρούσα διπλωματική εργασία έχει ως σκοπό να αναλύσει κάποιες από τις σύγχρονες θεραπευτικές προσεγγίσεις, αλλά και τις προκλήσεις που σχετίζονται με τη …
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Investigation of protein biomarkers in HIV positive and HIV negative associated DLBCL
… to 40% of all cases globally. The incidence of HIV-associated lymphoma has decreased since the introduction of combination antiretroviral therapy (cART) in the mid-1990s. However, NHL, especially DLBCL remains the most common cause of morbidity and mortality among people living with HIV/AIDS, …
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Charakterisierung membranverankerter HIV-Fusionsinhibitoren
… Peptide T-20 und C46-B inhibieren die für den HIV-Eintritt essentielle Fusion der viralen mit der zellulären Membran. Der in dieser Arbeit durchgeführte Vergleich der antiretroviralen Aktivität der membranverankerten Fusionsinhibitoren C46-A, C46-B und C46-C sollte zur Definition der …
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HIV: a biopsychosocial context
… into the phenomenon of growing older with HIV. It attends the experience of the first aging HIV cohort and tries to understand what it means for the participants to grow older with this particular condition. The study was conducted using semi-structured interviews and data was analysed …
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Factors affecting parental disclosure of HIV status to HIV-Positive children and adolescents
Disclosing the diagnosis of HIV or AIDS to a child is a controversial and emotionally-charged issue among health workers, parents and caregivers of these children.195 parents and guardians were enlisted for this cross-sectional and exploratory study. A survey questionnaire and one to one in-depth …
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Factors affecting parental disclosure of HIV status to HIV-Positive children and adolescents
Disclosing the diagnosis of HIV or AIDS to a child is a controversial and emotionally-charged issue among health workers, parents and caregivers of these children.195 parents and guardians were enlisted for this cross-sectional and exploratory study. A survey questionnaire and one to one in-depth …
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Religiosity and Engagement in HIV Care Among African American People Living with HIV
… to religious leaders, into engagement in HIV care [EIHC] for African American people living with HIV [PLWH]. METHODS: Data for this study were collected through semi-structured individual interviews with African American PLWH, four focus groups with church leaders/members, and two focus …
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Tobacco/HIV-1-Induced Myeloid Cell-Derived Extracellular Vesicles in HIV-1 Pathogenesis
… which is highly prevalent in people living with HIV/AIDS, has been shown to exacerbate HIV-1 replication, in part via cytochrome P450 (CYP)-induced oxidative stress. CYP enzymes metabolize cigarette smoke condensate (CSC), causing oxidative stress and cytotoxicity. Our previous studies have …
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Structural organization in 9-year-old HIV-infected children and HIV-exposed children
… (ART) in children, studies continue to report HIVrelated neurodevelopmental damage and delays. Neuroimaging and neuropsychological studies have identified brain regions and cognitive domains vulnerable to the effects of HIV infection and exposure in children. As most studies focus on a single …
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