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Showing 1 to 20 of 34 for “"HIFU"”.
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Treatment of brain cancer and ischaemic stroke utilising High Intensity Focus Ultrasound (HIFU) guide with MRI
In this thesis high intensity focused ultrasound (HIFU) is utilized for cancer treatment (thermal mode) and treatment of ischaemic stroke (mechanical mode). These two applications were investigated in vitro and in vivo models. MRI was utilized to monitor the lesions created by HIFU either in …
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Development of positioning devices for MRI-guided high intensity focused ultrasound (HIFU) for abdominal, thyroid and brain, tumours
High intensity focused ultrasound (HIFU) is a promising technology for a variety of therapeutic applications. This concept initiated in 1942 by Lynn Zwemer [1]. HIFU has long been known as a minimal invasive or non-invasive procedure that destroys tissue through ablation. However, it is only in …
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Shear-wave imaging guidance for high-intensity focused ultrasound therapy
High-intensity focused ultrasound (HIFU) has attracted many research interests during the last three decades (since 1980s) for the precision of this treatment in the field of medical oncology and brain surgery. Even though the precision of HIFU application/exposure is particularly high, the overall …
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Optimized pulsing of high-intensity focused ultrasound for enhanced therapeutic window
High intensity focused ultrasound (HIFU) provides a unique modality to perform non-invasive surgeries. The thermal ablation technique relies on focusing the non-ionizing acoustic wave within soft tissues to produce a small lesion. HIFU operations are typically attempted by continuous-wave (CW) …
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Propagation of High Intensity Focused Ultrasound through a Patient-specific Ribcage Model
… modelling of high intensity focused ultrasound (HIFU) treatment through ribcage using patient data is described. This is further tested experimentally to derive at various parameters which could be indirectly useful in defining amount of energy and alteration needed in treatment protocols for the …
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Passive monitoring of high-intensity focused ultrasound
High intensity focused ultrasound (HIFU) can provide a means of noninvasive ablation or hyperthermia of tissues such as tumors. Real-time monitoring of the progression of the field distribution of the HIFU transducer during treatment is important for localizing the intersection of the beam with the …
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Dynamics of smart materials in high intensity focused ultrasound field
… by using high intensity focused ultrasound (HIFU) as the external trigger. HIFU has a unique capability of maintaining both spatial and temporal control and propagating over long distances with reduced losses, to achieve the desired response of the smart material. Two categories of smart …
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Biomechanical Assessment and Monitoring of Thermal Ablation Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU)
… and High Intensity F-ocused Ultrasound (HIFU). HIFU is a non-invasive procedure aims to coagulate tissue thermally at a localized focal zone created with noninvasively emitting a set of focused ultrasound beams while the surrounding healthy tissues remain relatively untreated. Harmonic …
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Schallfeldformung zur Reduzierung der Behandlungszeit bei der Therapie mit hochenergetischen fokussierten Ultraschallwellen
… fokussierten Ultraschallwellen (HIFU, high intensity focused ultrasound) ist eine minimal invasive Methode, Tumorgewebe lokal thermisch zu zerstören. Als Ultraschallquellen werden meist hoch fokussierende Ultraschallwandler verwendet, die nur geringe Ablationsraten zulassen, was …
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Novel Plasmonic Nanostructures for Applications in Sensing, Imaging, and Controlled Release
… with high-intensity focused ultrasound: HIFU). Because it can penetrate more deeply into soft tissues than near-infrared light, HIFU is a potentially more effective external stimulus for rapid, on-demand drug release. The first system was based on nanocages covered with smart, …
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Cavitation monitoring and spatial mapping for pulsed high-intensity focused ultrasound enhanced drug delivery
High intensity focused ultrasound (HIFU) is an emerging non-invasive ablation modality, in which high amplitude ultrasound waves are focused inside the human body to thermally ablate or mechanically disrupt the tissue at the focus. Ultrasound-enhanced drug delivery is an active and promising area …
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Nichtinvasives Temperaturmonitoring mit der Magnetresonanz-Tomographie bei medizinischen Thermotherapien mit fokussiertem Ultraschall oder Laser
… auf hochenergetischem fokussiertem Ultraschall (HIFU) oder Laserinduzierter Thermotherapie (LITT). Für diese Verfahren ist eine genaue Kontrolle der Erwärmung mit Temperaturmessverfahren erforderlich. Das Ziel dieser Arbeit war die Entwicklung, Optimierung und Analyse der drei unterschiedlichen …
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Quantitative ultrasound assessment of thermal therapy in liver
… exposed to high-intensity focused ultrasound (HIFU) to produce a discolored region of permanent damage. These samples were scanned in the area of damage before and after HIFU exposure with a 20 MHz single element transducer. Samples in both experiments were preserved, and histology slides were …
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Novel Systems Physiology Instrumentation: Addressing Limitations in Heart Failure Reseearch
… failure for High Intensity Focused Ultrasound (HIFU) ablation in cardiac tissue. HIFU ablation offers a unique opportunity to develop effective strategies for noninvasive or minimally invasive treatment of atrial fibrillation and other arrhythmias. Despite its promises, current HIFU technology …
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Effects of high intensity focused ultrasound on the intervertebral disc
… was possible to heat intervertebral discs with HIFU delivered by 50 or 5 mm diameter ultrasound transducers. Finite element studies indicated that it would be possible to heat the disc to a temperature of 65ºC or above through an extradiscal minimally invasive procedure with a 5 mm diameter …
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Investigation of Microbubble-enhanced Mild Hyperthermia with Focused Ultrasound for Drug Delivery Enhancement
… performed via High Intensity Focused Ultrasound (HIFU) however, HIFU focuses energy onto a millimeter size area. Prior work has shown that adding microbubbles during HIFU can enhance the heating. It was suggested that there exists an optimal microbubble concentration that varies with respect to …
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Size Effect in Polymeric Materials: the Origins and the Multi-physics Responses in Ultrasound Fields
… actuated by high-intensity focused ultrasound (HIFU). Our computational studies are based on molecular dynamic (MD) simulations at the atomistic scale, and experimentally-validated finite element models at the bulk level. From bottom-up direction, molecular dynamics can reveal the mechanisms of …
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Experimental Study of Advanced Cryopreservation Strategies for the Cardiovascular System: Superiority of Vitrification over Standard slow Freezing in Murine Vessels and Efficacy of Ultrafast Rewarming by High-Intensity focused Ultrasound (HIFU) in Cardiac Recovery from Deep Hypothermia (-6ºC)
… the use of High-Intensity Focused Ultrasound (HIFU) in hearts enables the recovery of cardiac contractile function after deep hypothermia (-6 ºC), showing superior cellular viability and heart performance compared with traditional cold storage, thereby supporting its potential suitability for …
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Fast estimation model of pressure-temperature response for planning focused ultrasound surgery
High Intensity Focused Ultrasound (HIFU) is becoming a widely accepted modality for extracorporeal non-invasive hyperthermia and surgical procedures. Since ultrasonic transducers need to operate in various challenging body locations, the arrangement of their array elements can be optimized to …
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PHOTOREFRACTIVE CRYSTAL-BASED ACOUSTO-OPTIC IMAGING IN THE NEAR-INFRARED AND ITS APPLICATIONS
… heating from high intensity focused ultrasound (HIFU) therapy, providing a powerful method for noninvasively sensing the onset and growth of thermal lesions in soft tissues. A single HIFU transducer is used to simultaneously generate tissue damage and pump the AO interaction. Experimental results …
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