Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"HEYL"”.
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A Genomic Approach to Identify The Notch Pathway As A Putative Tumor Suppressor In Endometrial Cancer
… <p>Two of the ten genes validated, <em>HEYL</em> and <em>HES1</em>, are down-stream targets of the Notch signaling pathway. <em>HEYL</em> and <em>HES1</em> were identified by microarray and qRT-PCR to have a significant decrease in expression in endometrial carcinomas compared to normal …
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Biochemische Charakterisierung der basischen Helix-Loop-Helix-Transkriptionsfaktoren Hey1 und Hey2 sowie Untersuchung ihrer Rolle während der Herz- und Gefäßentwicklung
… Herzfehlern. Untersuchungen der Hey1- und HeyL-Expression in Hey2-Knockoutembryonen mittels RNA in situ Hybridisierungen zeigten keine Veränderungen im Vergleich mit dem Wildtyp. Daraus kann gefolgert werden, dass Hey1 und HeyL zumindest dort, wo sie nicht mit Hey2 coexprimiert sind, die …
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Scaling and Gating Attosecond Pulse Generation
High-order harmonic generation (HHG) provides the basis for attosecond light sources delivering coherent pulses in the extreme ultraviolet spectral region. Such light sources are employed for a variety of applications within imaging, attosecond spectroscopy, and high-precision frequency metrology. …
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Behavioural and Emotional Correlates of Age-Related Visual Decline : Contextual and Self-Regulation Perspectives
This cumulative dissertation presents five empirical papers dealing with behavioural, emotional, and contextual correlates of visual functioning in old age, and one empirical paper focusing on social context in middle and old age in general. Results are based on different samples of older adults. …
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Mikrostrukturierung von Hartmetallen mit UV-Laserpulsen im Nanosekundenbereich
In dieser Dissertation wurde der strukturierte Abtrag von Hartmetallen mit Laserpulsen im Nanosekundenbereich untersucht. Ziel war es über ein Verständnis des Gesamtprozesses von der optischen Absorption über den Einzelpuls- bis hin zum Volumenabtrag, eine Optimierung lasergefertigter Werkzeuge …
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Fostering Engagement for Students From Low-Socioeconomic Status Backgrounds Using Project-Based Mathematics
<p>In overcrowded urban high schools, students are dealing with many issues in and out of school. Issues at home paired with math curriculum that does not seem relevant to their lives, leads to a lack of engagement in the classroom.</p> <p>This research poses the question: How can project-based …
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Frauenbiografien, Generationenverhältnisse und Sorgestrategien - Eine qualitativ-rekonstruktive Studie zur Situation von Töchtern als betreuende und pflegende Angehörige
Demographischer Wandel und „Überalterung“ der Gesellschaft führen zu einem immensen Anstieg des Pflegebedarfs alter Menschen. Ein Großteil dieser Menschen wird zu Hause von pflegenden Angehörigen versorgt. Der oder die „pflegende Angehörige“ wurde jüngst vermehrt als wichtigster Leistungsträger im …
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The House Prostitute: A Case Study
Made available in DSpace on 2014-12-14T06:45:53Z (GMT). No. of bitstreams: 1 7606793.pdf: 15267105 bytes, checksum: b25fd2f4862b75bf7a6a1eb654a5d463 (MD5) Previous issue date: 1975
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The 'Southern Routeway' of The United States, a Study of Interregional Surface Freight Movements
Made available in DSpace on 2014-12-05T20:48:35Z (GMT). No. of bitstreams: 1 6303268.pdf: 4272096 bytes, checksum: bf1ad33afd1fc99354f391ad467a0cd2 (MD5) Previous issue date: 1962
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Phase Relations in the YBa2Cu3O7-x - SiO2 System and the Impact on Superconducting Fibers
This dissertation presents the first reported identification and analyses of the phase relations in the YBa2Cu3O7-x (YBCO)-SiO2 system at elevated temperatures. In this regard, a rigorous characterization study of the reaction phases within YBCO glass fibers, heat-treated YBCO+SiO2 pellets, rapid …
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THE ROLE OF NOTCH SIGNALING IN THE DIFFERENTIAL ABILITY OF SUPPORTING CELL SUBTYPES TO SPONTANEOUSLY REGENERATE HAIR CELLS IN THE NEONATAL MOUSE COCHLEA
… and in situ hybridization. The Notch effector HeyL was increased in the apical one-third of the cochlea while other Notch players are decreased. The most notable example is the Notch effector Hes5, which is directly responsible for inhibiting HC fate, and was reduced in outer pillar cells and …