Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"HEL"”.
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Type B Presentation from HEL Protein in the Context of Inflammation
… from the model antigen hen egg white lysozyme: HEL) are capable of binding MHC II in multiple conformations. Resting antigen presenting cells: APC) load peptide in early endosomal compartments where multiple conformations of a given pMHC pair are allowed, generating both type A and B pMHC …
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Hydrodynamic behavior and thermal stability of a PEGylated protein: Studies with hen egg lysozyme
… stability of a model protein---Hen Egg Lysozyme (HEL). HEL was modified with a linear, 20-kD, PEG to produce mono (PEG1-HEL), di (PEG2-HEL), and triPEGylated (PEG3-HEL) species.</p><p>The hydrodynamic properties of HEL were altered upon PEGylation. A decrease in sedimentation (s) and diffusion (D) …
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Processing of Exogenous Hen Egg-White Lysozyme for Presentation on Major Histocompatibility Complex Class I and II Molecules
… T cell epitope within hen egg-white lysozyme: HEL) that is presented on MHC class I via the cross-presentation pathway. The work in this thesis examines two issues: 1) CD8+ T cell cross-priming by subcutaneous immunization with exogenous HEL; and 2) cross-presentation of HEL to CD8+ T cell …
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Representations of the pagan afterlife in medieval Scandinavian literature
… Scandinavian realms of the dead, Valho˛ll and Hel. I first address the question of the nature of Hel which, according to Snorri Sturluson’s thirteenth-century mythography, was the name both of an underworld home of the dead, and a goddess who presided over that realm. Snorri’s sources diverge …
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Presentation Of Citrullinated Peptides Derived From Unmodified Protein By Antigen Presenting Cells.
… protein by antigen presenting cells. By Jamie Michelle Rimer Doctor of Philosophy in Biology and Biomedical Sciences: Immunology) Washington University in St. Louis 2010 Professor Emil R. Unanue, Chair Autoimmune responses to citrullinated proteins have been associated with rheumatoid arthritis; …
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Lautheitsbeurteilung in Abhängigkeit von der Stimulusart und vom vorangehenden Stimulus bei sequenzieller Darbietung der Reize
… mit der Lautheitsskalierungsmethode nach Heller getestet. Alle Probanden wurden auf ihre Normalhörigkeit untersucht und aus der Altersgruppe zwischen 20 und 30 Jahren rekrutiert. Es wurde in vier Versuchen jeweils einer von vier Stimulustypen im Freifeld angeboten. Die Pegel (30 dB bis 90 …
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Copper-catalyzed arylation of 1,2-amino alcohols. Synthesis of N-terminal, peptide helix initiators, and characterization of highly helical, capped polyalanine peptides
… advances in solubilization of polyalanine and helix stabilization by end capping were combined to synthesize a series of highly helical, water-soluble polyalanine peptides permitting straightforward context-free investigation of this most common helix- forming [alpha]-amino acid. Three types of …
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Experimental characterization of polyalanine helices in short and long contexts
… (CD), hydrogen exchange, and the t/c ratio of Ac-Hel, a helix stabilizing N-cap, are used in combination to quantify fractional helicity in order to determine the intrinsic helical propensity of an alanine residue, free from the hydrophobic packing within proteins. Constructed cross checks between …
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Charakterisierung der initialen Aufnahme des Kofaktors V (NAD) bei Haemophilus influenzae
… Das Außenmembranprotein e(P4), kodiert von dem hel-Gen, wurde als eine Komponente des Häminaufnahmesystems beschrieben. In dieser Arbeit wurde eine hel-Deletionsmutante hergestellt, anhand der nachgewiesen wurde, daß e(P4) als saure Phosphatase nicht an der Hämin-, sondern an der NAD-Aufnahme …
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High Strain Rate Properties of Geological Materials
… data was undertaken. Attempts at predicting the HEL were also partially successful. While no specific quantitative prediction method was found, it was noted that the HEL did seem to scale with grain size, in that the large grained materials had a lower value of the HEL (below 2 GPa) compared with …
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Genexpression des Adaptorproteins Shc bei Patienten mit Juveniler Myelomonozytärer Leukämie (JMML)
… und Gesunden, sowie in den Zellinien HEL, K562, HL-60 und Jurkat wurde mittels RT-PCR die Expression der mRNA von Shc gemessen. Die Expressionsniveaus von Shc zeigten nur bei den Zellinien HEL und K562 erhöhte Werte. Es wurde alternatives 'Exon Skipping' von Exon 12 beobachtet. Exon 12 …
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Power and energy storage requirements for ship integration of solid-state lasers on naval platforms
… States Navy's interest in high-energy lasers (HELs) dictates the need for further study into the propagation of laser light through different atmospheric conditions. Due to the amount of energy required to power these laser weapons systems and the limited amount of available energy onboard …
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The efficient and cost effective asynchronous mail sender for road warriors
… emails from different networks and then employed Hel techniques to design and evaluate a program aimed at solving these problems. The final program allows the user to set up and manage the connections the user connects to, and apply the SMTP settings specific to the current active connection to …
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Reinforcement Learning for Multi-modal Human-Robot Interaction
… Manager that learns to take the role of a helper (HEL) in a collaborative object-finding task, demonstrating high accuracy and user satisfaction through a comprehensive user study. Finally, we introduce IteraPlan, an iterative task-level planning framework that uses Large Language Models …
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First MeerKAT HI survey results mapping large scale structures hidden behind the Milky Way out to z = 0.08
… galaxies all the way at the VSCL distance (V(hel) ≈ 18 000 km/s), where we detected hints of two walls, and HI deficiency in the centre of VC04. GPS surveyed a long narrow strip (|b| ≤ 2°) along the Galactic plane, with the aim of penetrating the most obscured part of the ZoA. A segment of the …
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Μελέτη συσχέτισης του χρόνου επί της οθόνης με συναισθηματικές και συμπεριφορικές δυσκολίες σε παχύσαρκα παιδιά που ζουν στα νησιά της Άγονης Γραμμής
… (Strengths and Difficulties Questionnaire – SDQ-HEL), ένα έγκυρο εργαλείο για την αξιολόγηση συναισθηματικών και συμπεριφορικών προβλημάτων (Giannakopoulos et al., 2009). Πραγματοποιήθηκαν στατιστικές αναλύσεις για τη διερεύνηση διαφορών στις ψυχοκοινωνικές εκβάσεις μεταξύ ομάδων με διαφορετικό …
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”Bojkotta paraden i Jakobstad” : en jämförande studie av insändare om Jeppis Pride och Nykarleby Pride i Österbottens Tidning
… och efter paraderna. Jeppis Pride orsakade en hel del uppståndelse i Jakobstad, i övriga Finland och även utomlands. Artiklar, insändare och kommentarsfält vittnar om starka, splittrade åsikter. En del tycker att det inte är en dag för tidigt att ordna parad, medan andra vill att paraden ska …
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Design of potential antiprotozoal daunorubicin derivatives
… being intercalation into the DNA double hel~x and stimulation of superoxide radical formation. In order to discover the contribution of these mechanisms to trypanocidal activity, the trypanocidal potency of a series of daunorubicin analogues was assessed in vitro. The ability of these …
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Effects of GATA4-targeted compounds in hypertrophic models of hypoplastic left heart syndrome cardiomyocytes
… Havaitsimme myös, että HLHS-solulinja HEL 149 näytti poikkeavan kolmesta muusta solulinjasta siten, että sen geeniekpressioprofiili muistuttaa sydämen vajaatoimintapotilaissa nähtäviä muutoksia. Tämä havaittiin pääasiassa tilastollisesti merkitsevästi alhaisempana MYH6 geenin …
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Engineering and characterisation of anti-progesterone OBodies
… engineered to bind to Hen Egg-white Lysozyme (HEL) with nanomolar affinity as a proof-of-concept technology and has been given the name OBodies. This thesis explores this concept further with an OBody (D7) engineered to bind to the small molecule progesterone (P4) with potential applications to …
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