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Showing 1 to 2 of 2 for “"HAX-1"”.

  1. The Novel Role of Hematopoietic Lyn Substrate-1 Associated Protein X-1 in Cardiac Contractility and Cardioprotection

    … Lyn substrate associated protein-1 (HAX-1) was discovered in 1997 and suggested to play an anti-apoptotic role in B-cells. Although HAX-1 is ubiquitously expressed in all tissues, its role in the heart remains virtually unknown. Interestingly, recent studies demonstrate that HAX-1 …

    ohiolink Repository record for The Novel Role of Hematopoietic Lyn Substrate-1 Associated Protein X-1 in Cardiac Contractility and Cardioprotection (opens in a new tab)

  2. Novel Protein-protein Interactions Regulate The Proteolytic Activity Of The Pro- Apoptotic Serine Protease, Omi/htra2

    … at least two more known substrates of Omi, the HAX-1 and the ped/pea-15 proteins. HS1-associated protein X-1 (HAX-1) is a mitochondrial protein, degraded by Omi after induction of caspase-dependent apoptosis. Ped/pea-15 is also an anti-apoptotic protein and is cleaved by Omi after induction of …

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