Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"H4K8ac"”.
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Characterization of Chronic Glucocorticoid Exposure on Natural Killer Cell Function: A Model for Stress Induced Alterations on the Epigenetic Landscape
… upon cellular activation demonstrating increased H4K8Ac, increased accessibility of the chromatin structure, and concomitant loss of HDAC1 and HDAC3 at regulatory loci. These results demonstrate chronic GC exposure to impact NK effector function through the modification of the epigenetic status of …
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Microbiota regulate short chain fatty acids and influence histone acylations in intestinal epithelial cells.
The intestinal microbiota have a vital role in aiding digestion by metabolising dietary fibres. In this process, they produce short chain fatty acids (SCFAs) such as butyrate, an important energy source for intestinal epithelial cells. SCFAs are chemically related to histone acylations, a growing …