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Showing 1 to 1 of 1 for “"H452Y"”.
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Signal transduction by the 5-HT2A receptor and its H452Y polymorphic variant
… and signalling mechanisms of the 5-HT2AR and H452Y-5-HT2AR receptor variant. Both ARF1 and PLD1 have previously been shown to bind to the carboxy-terminal tail (ct) of the 5-HT2AR. In chapter three it is demonstrated that the 5-HT2AR can activate PLD in an ARF-dependent manner, primarily …