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Showing 1 to 1 of 1 for “"H3R42me2a"”.
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Discovery and Characterization of Methylation of Arginine 42 on Histone H3: A Novel Histone Modification with Positive Transcriptional Effects
… H3, the asymmetric dimethylation of arginine 42 (H3R42me2a). H3R42 is conserved through evolution and is at the DNA entry/ exit position within the nucleosome core, with likely interactions with the DNA backbone. I show that methyltransferases CARM1 and PRMT6 methylate this residue in vitro and in …