Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 78 for “"H1N1"”.
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A nutriceutical approach to inhibiting H1N1 influenza infection
… and human milk for anti-influenza virus (H1N1) activity. The results of these screening assays demonstrated that selected HMO were able to block virus infectivity but only at relatively high HMO concentration. The inhibitory concentration necessary to achieve 50% inhibition of infectivity …
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Printing the Pandemic: An Analysis of H1N1 Vaccine News Coverage
… coverage of the vaccination debate during the H1N1 pandemic in 2009. It explores how the agenda-setting press in North America framed the benefits and risks of vaccination: the key themes it emphasized, the sources whose voices it privileged and those it overlooked, and the cultural and …
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Predicting Mutational Pathways of Influenza A H1N1 Virus using Q-learning
… representing antigenic drifts within influenza A/H1N1 hemagglutinin (HA) protein as a graph, $G = (V, E)$, where $V$ is the set of vertices representing each possible sequence and $E$ is the set of edges representing single amino acid substitutions. Each transition is characterized by a Malthusian …
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Reverse Zoonosis of Pandemic A(H1N1)pdm09 Influenza Viruses at the Swine/Human Interface
<p>The 2009 pandemic influenza A(H1N1)pdm09 virus emerged from the swine population. Despite frequent zoonotic events, swine influenza viruses had not become established in humans previously and little is known about host-barriers which prevent swine influenza viruses from efficiently infecting …
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Geographic and demographic transmission patterns of the 2009 A/H1N1 influenza pandemic in the United States
… thesis describes how transmission of the 2009 A/H1N1 influenza pandemic in the United States varied geographically, with emphasis on population distribution and age structure. This is made possible by the availability of medical claims records maintained in the private sector that capture the …
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Risk Perceptions, Past Vaccination, and Vaccine Acceptance for Seasonal and Outbreak (2009 H1N1) Influenzas Among a University Sample
… to human life and well-being. The 2009 outbreak H1N1/A influenza virus also was expected to disproportionately affect healthy, young persons under the age of 25 years. However, acceptance and uptake of preventive health behaviors among this cohort is poorly understood, thus precluding a …
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Pandemia Nueva Influenza A (H1N1): un análisis de plan de contingencia para pandemia de influenza de la República Argentina
Esta tesis solo está en formato papel por lo que se debe consultar en la propia Biblioteca Di Tella. La consulta se hace solo bajo reserva escribiendo a serviciosbiblio@utdt.edu.
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The Molecular Basis of Fitness and Transmissibility of Neuraminidase Inhibitor Resistant Influenza A Viruses
… solely linked to NA H275Y variants of seasonal H1N1 viruses, and they are referred as the naturally resistant viruses. A big question remains open about what fundamental molecular changes in the seasonal H1N1 viruses led to the surge of the naturally resistant viruses. When this question …
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Pandemic Potential of Reassortant Swine Influenza A Viruses
… While the previously circulating classical swine H1N1 influenza virus lineage was very stable in the swine population, triple reassortant lineage viruses have supplanted the classical H1N1 lineage and undergone repeated reassortment events, acquiring HA and NA genes from human, swine, and avian …
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Estimating network structure and propagation dynamics for an infectious disease : towards effective vaccine allocation
… influenza outbreak, such as the 2009-2010 H1N1 "Swine Flu" episode, it is crucial to effectively allocate limited resources in order to minimize the casualties. Design of effective resource allocation strategies requires good understanding of the underlying contact network and of the …
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Host Modulators of the Death Response to Influenza A Infection
… components that are subverted to support H1N1 influenza A virus infection of human mucosal epithelial cells. Integration across relevant public data sets exposed druggable gene products required for epithelial cell infection or required for viral proteins to deflect host cell suicide …
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INTERSPECIES TRANSMISSION AND HOST RESTRICTION OF INFLUENZA A VIRUSES
… triple reassortant internal genes, and pandemic H1N1 lineage NP and M genes. The reassortant H1N2 viruses were antigenically different from the classical and the contemporary TR H1N1 swine influenza viruses (SIVs). The reassortments of pandemic H1N1 with circulating SIVs points out the potential …
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Pandemic panic : a network-based approach to predicting social response during a disease outbreak
… of disease and social response during the 2009 H1N1 outbreak in Mexico City, the 2003 SARS and 2009 H1N1 outbreaks in Hong Kong and the 2012-2013 Boston influenza season, accurately predicting population-level behavior. The effect of interventions on the disease spread and social response is …
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Étude du clivage de l'hémagglutinine de l'influenza par la matriptase
… de façon protéolytique l’hémagglutinine de virus H1N1 mais pas celle de virus H3N2 dans des modèles cellulaires d'épithélium bronchique. La microscopie confocale a également montré la colocalisation du virus de l’influenza avec la matriptase dans les endosomes lors de l’entrée du virus dans la …
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FMF assay for assessing vaccine generated antibodies in a biomimetic manner
… tested using two different subtypes of viruses H1N1 (A/Puerto Rico/8/1934 and A/Brisbane/59/2007), and H3N2 virus (A/Aichi/68) with their respective subtype specific stem specific monoclonal antibodies: M145, Aca-1, Aca-2 (H1N1 specific) and Aca-3 (H3N2 specific). Subtype specific mAbs blocked …
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Mathematical modelling of emerging and re-emerging infectious diseases in human and animal populations
… avian influenza outbreak and of the 2009-2010 H1N1 pandemic influenza. From an applied perspective, parameter estimation is a key part of the modelling process and in this thesis statistical inference has been performed within both a classical framework (i.e. by maximum likelihood and least …
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The Epidemiology and Control of Human Influenza in Vietnam
… data. I also conducted a study of influenza A/H1N1 transmission within households. ILI notifications in Viet Nam show a latitudinal gradient, with seasonality in the north but no seasonal pattern observed in low lying areas of central and southern Viet Nam. Seasonality is however observed in …
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Molecular Evolution of Viruses
… Influenza A Virus.</p> <p>The recent Influenza A/H1N1(2009) outbreak has been the focus of intense research because of its high level of infectivity across the globe. Analysis of nucleotide sequence polymorphism in the genomic segments encoding the two most immunologically important proteins of …
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Modeling reduction of pandemic influenza using pharmaceutical and non pharmaceutical interventions in a heterogeneous population
… Flu" of 1918 and the more recent 2009-2010 H1N1 "Swine Flu" scare, pharmaceutical as well as non-pharmaceutical resources are limited in availability and effectiveness. In this thesis we apply OR methods to evaluate the effectiveness of such resources and the strategies for reducing the …
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