Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"H-NS"”.
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H-NS Counter-silencing as a Primary Regulatory Mechanism of Curli Gene Expression in Salmonella Typhimurium
… of horizontally acquired genes into transcriptional networks is essential for regulated expression of virulence in the bacterial pathogen Salmonella enterica serovar Typhimurium. The nucleoid-associated protein H-NS is able to recognize and bind AT-rich horizontally acquired genes, such …
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Studies on the Role of Histone-like Proteins in Gene Regulation in Uropathogenic Escherichia coli Isolate 536
In this study, the role of histone-like proteins in gene regulation in uropathogenic Escherichia coli isolate 536 was monitored. The histone-like nucleoid structuring protein H-NS is a global regulator in Escherichia coli that has been intensively studied in non-pathogenic strains. No comprehensive …
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Functional Characterization Of The Cholera Toxin Promoter Of vibrio Cholerae
<p> <i>Vibrio cholerae</i> is the bacterium responsible for the severe diarrheal disease cholera. The disease is directly caused by cholera toxin, which is secreted by the bacterium in the upper small intestinal lumen during the course of infection. Expression of cholera toxin, along with other …
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Super-Resolved Microscopy as a Tool to Unveil Intracellular Structure in Biological Systems
… of the heat-stable nucleoid structuring (H-NS) protein within E. coli in response to high osmolarity. H-NS is an abundant nucleoid association protein in gram-negative bacteria and plays a dual role as a global gene regulator and nucleoid organizer. By imaging the spatial organization of …
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Transcriptional regulation in Salmonella enterica by the Lysr-type factor LeuO
… al nucleoide (NAPs), entre las cuales destaca H-NS, que además de conferir estructura al cromosoma tiene un papel esencial en la regulación de genes situados en las zonas a las que se une. Dichas zonas poseen un bajo porcentaje de G+C, que es una característica habitual de regiones adquiridas por …
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Nucleoid-Associated Proteins of Streptomyces coelicolor: Discovery and Functions
… product discovery as these clusters are often transcriptionally silent (“cryptic”) under normal laboratory conditions, making the initial characterisation and heterologous expression of the products they encode problematic. The role of the architectural nucleoid-associated proteins (NAPs) in …
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Molecular Electronic Structure via Photoelectron Imaging Spectroscopy
… an emphasis on photoelectron angular distributions. Experimental ion generation, mass selection, laser photodetachment, and photoelectron ion imaging were all done in a photoelectron imaging spectrometer described in detail. Results from simplistic systems, OH- and CH-, are used to illustrate the …
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Nucleoid condensation in Escherichia coli by the DNAbinding protein SymE
… its cognate toxin. Type I TA systems consist of a toxic protein and an RNA antitoxin which interacts directly with toxin mRNA to prevent its translation. The toxins of all but two type I TA systems are small proteins that imbed into the inner membrane where they generally oligomerize and …
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Expression of the multi-drug efflux genes acrAB of Escherichia coli
… system of Escherichia co/i, is largely responsible for the increased intrinsic resistance of this organism to many antimicrobial agents. The level of mRNA specific to the acrAB efflux genes is elevated by six-fold during exponential phase of growth in LB broth. In MOPS minimal medium …
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Characterization of Bacterial Transcriptional Regulatory Networks through Genome-Wide in vitro Run-Off Transcription RNA-Seq (ROSE)
The current methods for characterizing transcriptional regulatory networks are limited to in vivo conditions, providing a snapshot of multiple regulatory interactions simultaneously. To complement these approaches, a new method called ROSE (Run-Off transcription/RNA-sequencing) has been developed …