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Showing 1 to 1 of 1 for “"H/ACA snoRNP"”.

  1. Distinguishing features of guide and substrate RNA recognition by H/ACA snoRNPs

    Kelly, Erin Katelyn, University of Lethbridge. Faculty of Arts and ScienceLethbridge, Alta. : Universtiy of Lethbridge, Department of Chemistry and Biochemistry2018

    H/ACA small nucleolar ribonucleoproteins (snoRNPs) pseudouridylate RNA in eukaryotes and archaea. They consist of four proteins and a guide RNA. It is unclear which element of the guide RNA the H/ACA proteins recognize. By designing guide RNA variants with altered structural features, I determined …

    lethbridge Repository record