Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Gynaecological cancer"”.
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An exploration of symptom burden among breast and gynaecological cancer patients accessing care at University of Ilorin teaching hospital, Ilorin, Kwara State, Nigeria
Background: Breast and gynaecological cancers are the leading causes of cancer morbidity and mortality among women in developing countries. Advanced stage diseases with limited availability for treatment imply significant symptom burden; the relief of which poses a challenge for the health care …
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BMP9 Signalling in Ovarian Cancer
Ovarian Cancer is the 5th most common cause of cancer death in women and the second most common gynaecological cancer in the UK. Worldwide, around 152,000 women were estimated to have died from ovarian cancer in 2012. Survival rates for women with epithelial ovarian cancer have not significantly …
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Significance of Altered Golgi Apparatus and Cell Fusion Events in Ovarian Cancer Cells
Ovarian cancer is one of the most lethal gynaecological cancer. Heterogeneity associated with this cancer can be partially attributed to cancer cells being highly multinucleated and polyploid in nature. Stress-induced cytotoxic effects of cisplatin - a chemotherapy drug used to treat ovarian …
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Prevalence of gynaecological disease in women with an HMLH1 mutation in the Northern Cape province: Survey of a population with Lynch Syndrome in South Africa
… called hereditary non-polyposis colorectal cancer (HNPCC), is one of the most common hereditary cancer syndromes with an association with gynaecological cancers. Members of affected families have an increased risk for colon cancer as well as extra colonic sites; in particular endometrial and …
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Biomarkers of Genome Instability and Disease Progression in Ovarian Cancer
… (HGSOC) is the most common subtype of ovarian cancer and the major cause of gynaecological cancer-related deaths in the Western world. Overall survival for HGSOC patients has not improved over the last two decades, and the progressive evolution of chemotherapy resistance is common. The …
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Investigating the effect of conventional chemotherapies, Cisplatin and Doxorubicin, in combination with a nuclear transport inhibitor, INI-43, on cerfical cancer cells
Background: Cervical cancer is the most common gynaecological cancer in South Africa, and the burden of disease remains high across the developing world. Like with many other cancers, treatment is limited due to drug resistance and adverse side effects. To overcome these limitations, it has become …
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The Utility of CA125 for the Detection of Ovarian Cancer in Primary Care
Background Ovarian cancer is the 6th most common cancer to affect UK women and has the worst prognosis of any gynaecological cancer. Most women are not diagnosed until the disease is advanced, which leads to poor outcomes. Earlier ovarian cancer diagnosis has the potential to improve these …
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A retrospective audit of young patients diagnosed with cervical cancer over ten years at Groote Schuur Hospital, Cape Town between 1 January 2003 and 31 December 2012, and their outcome at five-year follow-up compared to women in the prior decade
Background : Cervical cancer is the second commonest gynaecological cancer amongst women worldwide and the leading cause of cancer deaths in developing countries – contributing 83% of new cases and 85% of all deaths annually to the burden of this disease. Information and awareness of this illness …
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Developing Novel Conservative Treatments For 2 Endometrial Cancer By Targeting Aquaporin-1
Endometrial cancer (EC) is sixth most common cancer among females worldwide and 186 the most common invasive gynaecological malignancy. Pathogenesis of endometrial cancer is related to prolonged elevated levels of oestrogen due to obesity, nulliparity, and polycystic ovaries leading to uncontrolled …