Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 70 for “"Gut-Brain"”.
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Multifunctional Wireless Gut-Brain Neurotechnology
The complexity of the brain is well known, in that it uses specially organized neural circuits to interact with the external world. Besides external stimuli, the brain also receives, integrates, and responds to sensory signals emerging from internal organs of the body through the network of the …
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Gut-brain interactions in food reward
… of abuse, the speed at which a drug reaches the brain affects its abuse potential; this is known as the "rate hypothesis." Here, we test whether the rate hypothesis of addiction may apply to food, specifically whether caloric availability, or the speed at which carbohydrate becomes available for …
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Modulation of the microbiota-gut-brain axis by fermented foods
The gut harbours trillions of microbes that are involved in robust communication with the host. Various intrinsic and extrinsic factors modulate the composition of the gut microbiota. Over the past two decades seminal work on the impact of diet in shaping gut microbiota composition has resulted in …
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Unravelling the impact of pesticides on the microbiota-gut-brain axis
The gut microbiota exists within a dynamic ecosystem influenced by various factors, including exposure to xenobiotics such as pesticides. There is an increasing emphasis on the role of the gut microbiota in maintaining host health, including growing evidence for its role in regulating brain …
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Effects of hydration physiology on aspects of the gut-brain axis
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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Investigation of non-traditional roles of the neural gut-brain axis
The neural gut-brain axis is an important bidirectional pathway through which the gastrointestinal (GI) tract communicates with the central nervous system (CNS). This axis includes sensory nerves that send information from the GI tract to the brain and motor nerves that transmit descending …
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The Microbiota Gut Brain Axis in the Neuropsychological Complications of Chemotherapy Treatment
… causes both neuroinflammatory changes within the brain, a neuropathological hallmark shared by all neuropsychological symptoms, and significant compositional changes to the gut microbiota. However, the role of the microbiota-gut-brain axis in the development of neuropsychological complications …
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Novel insights into early life stress-induced dysfunction of the gut-brain axis
… pain, a debilitating hallmark of disorders of gut-brain axis interactions such as irritable bowel syndrome, has a major impact on quality of life. Given the increasing prevalence of irritable bowel syndrome over the past number of years, as well as a lack of effective treatments for disorders …
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Unravelling the impact of early-life nutrition on microbiota-gut-brain axis signalling
… childhood, are essential for optimal growth, brain and immune system function. Growing lines of evidence suggest that gut microbiota play a role in immune system education, brain function and behaviour. Disruptions in the gut microbiota composition during critical periods of development …
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Nutritional psychiatry, stress and the microbiota-gut-brain axis: focus on dietary fiber
… has an assortment of health benefits and the gut microbiota has been shown to be an integral regulator of brain function and behavior. The interface between these features may have implications from a therapeutic as well as a neurobiological perspective in terms of mental health function, …
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Mining the microbiome for markers of microbiota-gut brain communication and mental health
… acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the microbiota-gut-brain axis. While our techniques to measure the presence and abundance of these microbes …
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Gut-brain axis: Central impact of gut peptides and metabolic drug on monoamine neurotransmission
… hormones but can also modulate important brain function, unrelated to feeding behaviour and glucose homeostasis. Different evidence suggests that these peptides, as well as synthetic insulin secretagogue such as tolbutamide, can affect cognition, motivation, addiction as well as neuronal …
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The gut-brain axis in seizure susceptibility: A role for microbial metabolite S-equol
… and epilepsy. The microbes that inhabit gut mucosal surfaces, termed the gut microbiota, have been increasingly implicated in the pathology of neurological diseases including epilepsy. This gut-brain axis is an intriguing therapeutic target in epilepsy as gut microbes can affect the CNS …
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From youth to old age: therapeutic potential of microbiota interventions in the gut-brain-axis
… a growing recognition of the involvement of the gut microbiota in the regulation of certain physiological and metabolic parameters across the life cycle of animals. A greater understanding of the microbiota changes throughout the life cycle may provide a novel therapeutic target for treating …
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The microbiome-gut-brain axis in preclinical alpha-synuclein models of Parkinson's disease
… degeneration of the nigrostriatal pathway in the brain, causing motor dysfunction, and the build-up of α-synuclein protein fibrils throughout several brain regions. Many PD patients report a number of gastrointestinal (GI) symptoms some of which can precede motor symptoms. α-synuclein is detected …
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Decoding the interplay between the microbiota-gut-brain axis and the hypothalamic regulation of eating behaviour
… perspective we postulate a key role for the gut microbiota and its metabolites in the “priming” effects of this exposure. Increased food manipulation, or food crumbling behaviour was observed in a sex-specific manner (Chapter 2). The exposure to a HFHS diet during early-life had specific …
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Exploring INSL5 and RXFP4 in the gut-brain axis and their potential role in feeding behaviour
… a peptide hormone secreted from the distal gut, and its cognate receptor, relaxin/insulin-like family peptide receptor 4 (RXFP4), have been implicated in feeding in animal models. Administration of INSL5 and chemogenetic manipulation of Rxfp4-expressing cells influence feeding behaviour in …
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Exploring glucagon-like peptide 1-secreting L-cells as signal transducers in the microbiota-gut-brain signalling pathways
Background: Communication across the microbiota-gut-brain axis is integral to homeostatic functions throughout the body. However, the mechanisms behind this communication network have yet to be fully elucidated. There is mounting evidence that bacterially secreted metabolites, such as short-chain …
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