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Showing 1 to 3 of 3 for “"Gut Mucosal Immunity"”.

  1. Impact of HIV infection on the frequency and phenotype of Th17 cells in the female genital tract

    … have recently been implicated in regulating gut mucosal immunity during HIV infection by sustaining gut mucosal barrier integrity, although they do not respond to HIV directly. Depletion of Th17 cells from the gut mucosa during HIV infection has been suggested to contribute to elevated …

    cape-town Repository record for Impact of HIV infection on the frequency and phenotype of Th17 cells in the female genital tract (opens in a new tab)

  2. Regulation of the beta7 integrin gene in T cells: role of the MAPK signalling pathways

    … αEβ7 have evolved to play specialized roles in gut mucosal immunity. α4β7 mediates the homing of lymphocytes to intestinal Peyer's patches, mesenteric lymph nodes, and the lamina propria by binding to the vascular addressin MAdCAM-1 (Fong et al., 1997). αEβ7 binds epithelial E-cadherin retaining …

    auckland-ms Repository record for Regulation of the beta7 integrin gene in T cells: role of the MAPK signalling pathways (opens in a new tab)

  3. Modulators of Innate Gut Immunity to Enteric Viral Infections: Murine Norovirus (MNV) as a Model

    … has a significant impact on the efficiency of gut immunity in responding to infectious pathogens, as reflected by the increased burden of gastrointestinal infections at the extremes of age. In this thesis, using the Murine Norovirus (MNV) oral infection model, I aimed to characterize intestinal …

    cambridge Repository record for Modulators of Innate Gut Immunity to Enteric Viral Infections: Murine Norovirus (MNV) as a Model (opens in a new tab)