Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Gut–liver axis"”.
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Engineered Liver and Intestine Platforms for Modeling Physiology and Disease
The intestine and liver are connected in vivo via a recirculating blood supply called the gut-liver axis, which plays a critical role in nutrient/drug absorption and metabolism. Given the diversity of roles the liver plays, there is a need for robust in vitro models capable of recapitulating …
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Follow your gut: Does AKR1D1 impact gastrointestinal health?
Dysfunction of the gut-liver axis contributes to non-alcoholic fatty liver disease (NAFLD) pathogenesis and progression. Bile acid homeostasis is disrupted in NAFLD, and this has been suggested to increase cytotoxic bile acids species in the intestine, disrupt cytoprotective intestinal bile acid …
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Composición de la microbiota en pacientes pediátricos con déficit de hormona de crecimiento antes y después de recibir tratamiento con hormona de crecimiento
… body, the most numerous and complex being the gut. Alterations in the composition and functionality of the microbiota (dysbiosis) have been associated with various pathologies. Among the different functions of the microbiota, its role in growth is particularly important. Indeed, several studies …
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Machine learning and data analytics for liver disease modeling
… (PSC) is a rare, progressive cholestatic liver disease characterized by bile duct inflammation, hepatic fibrosis, and a markedly increased risk of malignancy. Despite its severity, the underlying pathophysiology of PSC remains incompletely understood, and effective medical therapies remain …