Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Guillain-Barre"”.
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Guillain Barre Syndrome (GBS) in Cape Town, South Africa: a descriptive outcomes cohort study
INTRODUCTION Guillain-Barré syndrome (GBS) or acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is an important cause of acute severe and life-threatening weakness. It occurs worldwide and may affect all age groups, but varies widely in clinical presentation, subtype, …
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Spinal compression in childhood : the University of Cape Town experience
… non-compressive causes of paraplegia, such as Guillain-Barre Syndrome and poliomyelitis.
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MODULATION OF VOLTAGE-GATED CALCIUM CHANNEL BY A SYNAPTIC PROTEIN AND GANGLIOSIDE
… against ganglioside are found in patient sera of Guillain-Barre syndrome, though the underlying pathogenesis is not clear yet. We discovered that anti-ganglioside antibodies modulated voltage sensing of the Ca2+ channel. The opening threshold of voltage-gated calcium channel are either reduced or …
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Development of an Attenuated Zika Virus by Editing the 5’ Untranslated Region
… severe neurological effects in adults, such as Guillain-Barre Syndrome (GBS), and in infants whose mothers acquired the virus during pregnancy, causing Congenital Zika Syndrome (CZS). Currently, no approved vaccine is available and there is a critical need to develop an effective and safe …
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Neuro-zika: Brain structure and functional organization of adult humans with zika virus infection and severe neurological complications
… While these complications often present as Guillain-Barre Syndrome (GBS)-like manifestations confined to the peripheral nervous system (PNS), they extend to symptoms of the central nervous system (CNS) in a subset of severely affected patients. Yet, reports on the adult CNS have remained …
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Statin-Mediated Attenuation of Chemokine Expression in Peripheral Nerve Vascular Endothelial Cells
… play a pivotal role in the pathogenesis of Guillain-Barré Syndrome (GBS), a debilitating autoimmune disorder that affects the peripheral nervous system. By up-regulating endothelial expression of chemokines and cell adhesion molecules (CAMs), TNF-α facilitates the recruitment and trafficking …
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DISSECTING THE MOLECULAR MECHANISMS RELATED TO THE ONSET OF NEUROLOGICAL COMPLICATIONS IN THREE CELLULAR MODELS OF SARS-COV 2 INFECTION: IPSC-DERIVED MOTO R NEURONS, IPSC-DERIVED DOPAMINERGIC NEURONS, IPSC DERIVED-HUMAN CORTICAL ORGANOIDS.
… but also peripheral disorders including Guillain-Barre syndrome and myositis-like muscle injury [2, 4–8], suggesting detrimental effects of SARS-CoV-2 on both the central and peripheral nervous system (CNS, PNS). Multiple studies have shown neuroinflammation in patients with COVID-19, …
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Forced-Exercise Dependent Changes in Cellular Immunity: Effects on Experimental Autoimmune Neuritis
<p>Guillain-Barré Syndrome (GBS) is a debilitating inflammatory autoimmune disease of the peripheral nervous system that is characterized by rapid-onset paraparesis with areflexia progressing to neuromuscular paralysis. The most common form of GBS observed in North America and Europe is acute …