Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Growth cone guidance"”.
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Growth Cone Pathfinding and Neuromuscular Synaptogenesis in Drosophila Midline Mutants
… how abnormal midline decisions affect subsequent growth cone pathfinding. Results showed that despite abnormal decisions at the midline, subsequent pathways and synaptic targeting in all cases were the perfect mirror-images of those seen in wildtype. This suggests that a growth cones' particular …
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Investigating the Role of MicroRNAs in Regeneration and Axonal Pathfinding
… so, axons utilize a specialized structure, the growth cone, which senses and interprets guidance cues in its surrounding environment to change the direction of axonal outgrowth. MicroRNAs, which regulate mRNA translation, have recently been shown to regulate both neurite outgrowth and growth …
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Retinoic Acid and the Underlying Cellular Mechanisms involved in Neurite Outgrowth and Growth Cone Turning during Regeneration
… as well as tropic effects to guide neurite outgrowth. Cultured neurons of the Lymnaea central nervous system (CNS) have previously been used to investigate the role of RA in neurite outgrowth and growth cone guidance. Recently however, a novel phenomenon has been identified, in which neurite …
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Myosin 10 is Required for Spinal Motor Axon Growth and Guidance in Zebrafish Embryos
… grow towards their specific target organs at growth cones, by sensing the environment for molecular cues which reorganizes their cytoskeleton to allow for their growth. Growth cones are actin rich suggesting that actin binding molecules play a vital role in axon guidance. Myosins are a class …
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Elucidation of the Retinoid Signalling Pathway Involved in Axon Guidance in Lymnaea stagnalis and Xenopus laevis
… Moreover, RA has been shown to act as a guidance molecule for growth cones of regenerating motorneurons of the pond snail, Lymnaea stagnalis. Our lab has recently shown that RA can induce this morphological response independent of nuclear transcription, however, the role of the retinoid …
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Local Protein Turnover As a Regulatory Mechanism of Growth and Collapse of Neuronal Growth Cones
Der axonale Wachstumskegel reagiert außergewöhnlich empfindlich auf chemische und mechanische Umgebungseinflüsse, was lokale, autonome Reaktionen hinsichtlich der Wachstumskegel-Morphologie ermöglicht. Abhängig vom jeweiligen Stimulus kann Wachstum auf der einen Seite, oder Kollaps des …