Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Growth Inhibitors"”.
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Partial Characterization of Animal Growth Inhibitors from Soybeans
… G-25 column in efforts to isolate the animal growth inhibitors present soybeans. Each fraction was added to the diet of growing mice and growth inhibition (GI) activity was determined by comparing their_ growth rates to g1"'owth rates achieved on an autoclaved soybean meal diet. Fractions I …
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Sephadex G-25 and Charcoal Separation of Mouse Growth Inhibitors in Soybeans from Trypsin Inhibitors
… isolate and purify a small molecular weight growth inhibitor from soybeans and to gain needed knowledge about its properties. Once this growth inhibitor is identified, appropriate methods of inactivating or removing the inhibitor may be developed, so that much, if not all of the soybean why …
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Combination of Dietary Tomato and Broccoli Powders Are Effective Growth Inhibitors of Dunning R3327-H Prostate Adenocarcinomas
Tumor growth suppression was associated with reduced proliferation and increased apoptosis, as quantified by Proliferating Cell Nuclear Antigen (PCNA) immunohistochemistry and the ApoptagRTM assay, respectively. Utilizing real time polymerase chain reactions (RT-PCR) and the SYBR Green assay, mRNA …
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Role of growth inhibitors in nucleation and growth of thin film deposited by chemical vapor deposition in high aspect ratio structures
… is to identify, and understand the role of, growth inhibitors in the nucleation and growth of thin films by chemical vapor deposition (CVD). We focus on steady state processing methods using stable molecules in order to change thin film surface morphology in a controlled manner in high aspect …
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Risk Assessment for Listeria monocytogenes in Ready-to-eat Meat and Poultry Products
… and product formulation with microbial growth inhibitors. The dynamic in-plant model served as an input into the risk assessment model developed by the FDA and FSIS in 2003 which predicts the number of deaths and illnesses resulting from the use of each control method. The use of growth …
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The effect of potential anticancer gene products on breast cancer cell lines
… conditioned media containing single proteins on growth of human and mouse breast cancer cell lines was measured and compared to commercially available agents. Mesenchymal stem cells (MSCs) have been shown to home to tumors and are under investigation as vehicles for delivering anticancer gene …
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Preparation and stability of organic nanocrystals. Experimental and molecular simulation studies.
… anti-malarial artemisinin. The choice of crystal growth inhibitors/stabilizers was found to be critical and specific for each drug. The effect of the process variables, temperature, stirring rate, and the solute solution infusion rate into the anti-solvent, was rationalized in terms of how these …
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Inhibition of Calcium Oxalate Monohydrate Crystallization Using Organic Growth Modifiers
… to quantify both the efficacy and potency of growth inhibitors. These studies demonstrated that increased number of hydroxyl and carboxyl groups play a crucial role in interacting with specific COM crystal surface. Designing effective inhibitors require a fundamental understanding of …
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Are Barley Dwarfing Genes Important in Tolerance to Abiotic Stress?
DELLA proteins are a highly conserved group of growth inhibitors, mutants of which were integral to the semi-dwarf, high yielding wheat lines of the Green Revolution. In addition to reducing plant growth, the gain of function (GoF) mutants in which DELLA protein is stabilised were shown to confer …
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Control of Reaction Surface in Low Temperature CVD to Enhance Nucleation and Conformal Coverage
… the technology. However, it turns out that most growth precursor molecules can not fulfill both the requirements. For good nucleation characteristics, it is required that the precursor has a high sticking probability on the substrate, whereas, for conformal deposition, the sticking probability of …
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A study of the "Phoenix phenomenon" in Clostridium perfringens
… age of inoculum, anaerobiosis, assay medium, growth inhibitors, and diluent were studied. The "Phoenix phenomenon" was reproduced in experiments using sporulation negative mutants derived from HT₉, various ages of inocula, and under strict anaerobic conditions. Similarly, all of the assay …
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Hormonal regulation of phosphatidylcholine metabolism in Apium graveolens
Previous studies using plant growth inhibitors and gibberellic acid led to the hypothesis that two pools of phosphatidylcholine exist within the plant cell; one capable of producing signals involved in cell proliferation and the other capable of releasing signaling molecules which facilitate cell …
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Preclinical Studies of A Novel Idh1 Inhibitor In Acute Myeloid Leukemia (Aml)
… a block in cell differentiation, and tumor growth. Inhibitors of IDH1 mutant enzyme reduce 2-HG levels and release the differentiation block allowing AML cells to achieve terminal maturation. Recently, Ivosidenib (AG120), an IDH1 inhibitor, has been FDA approved for relapsed and newly …
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Crystallization of calcium sulphate during phosphoric acid production : improving filtration through improvement in particle shape and size distribution
… literature focuses on their sole role as growth inhibitors and has neglected their potential impact on altering solution speciation. Past studies on gypsum crystallization in phosphoric acid solutions usually involve the study of crystal growth and nucleation kinetics. However, most of …
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Novel synthetic methodology employing organosulfur chemistry in the synthesis of chalcone derivatives
… testing and were found to be extremely potent growth inhibitors. The third chapter details the experimental procedures used in this work and describes the spectroscopic details of all of the compounds synthesised in this body of work including full characterisation of all novel compounds.
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Cyclodextrin-based rotaxanes for material science applications
… structures/packing, morphology and crystal growth behaviour were explored. Encapsulation of profluorescent nitroxides through rotaxane formation demonstrated the use of CD-based rotaxanes to change the reactivity of CD guests and therefore preserve their properties. In Chapter 2, the …
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Cyclodextrin-based rotaxanes for material science applications
… structures/packing, morphology and crystal growth behaviour were explored. Encapsulation of profluorescent nitroxides through rotaxane formation demonstrated the use of CD-based rotaxanes to change the reactivity of CD guests and therefore preserve their properties. In Chapter 2, the …
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Ice control by antifreeze proteins: From interfacial thermodynamics, and engulfment resistance, to thermal hysteresis activity using theory and computation
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
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Further Exploring the Structure Activity Relationship (SAR) of MMV008138 and MMV1803522
… none of these new compounds were potent growth inhibitors of Dd2 strain P. falciparum. We conclude that the lead goes into a well-defined pocket within the PfIspD enzyme that only accommodates 2,4-dihalogenated phenyl D-rings. This pocket also cannot accept any substitution larger than F …
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Targeting final steps of sugar nucleotide biosynthetic pathway against <i>Aspergillus fumigatus</i>
… with cell wall synthesis would inhibit the growth of A. fumigatus. Biosynthesis of cell wall carbohydrates is carried out by Leloir glycosyltransferases, which are membraneembedded enzymes that convert sugar nucleotides to cell wall carbohydrates. Therefore, targeting Leloir …
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