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Showing 1 to 8 of 8 for “"Growth Hormone Receptor"”.
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A functional analysis of growth hormone receptor promoter regions in swine
[EMBARGOED UNTIL 08/01/2026] Growth hormone (GH) and its receptor (GHR) play critical roles in regulating growth, development, and reproductive function in animals. GHR expression in the liver is critical for postnatal growth and is regulated by tissue-specific promoters. While promoter 1 (P1) is …
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Investigating the role of growth hormone receptor in oesophageal squamous-cell carcinoma.
… diagnostic techniques and therapies. The growth hormone (GH) signalling axis is important for proper cellular and organ system function. The axis has been shown to play a role in a number of cancers.
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Analysis of the Relationship Between Growth Hormone Receptor Polymorphism rs6180 and Craniofacial Morphological Changes Associated with Herbst Appliance Therapy
Craniofacial growth results from both environmental and genetic factors over time. It would be exciting to isolate genetic factors that influence treatment responses from patients undergoing orthodontic treatment. Genetic genotyping and analysis of orthodontic patients is a new technologic …
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Verifying the Deletion of Growth Hormone Receptor Using a Quantitative Polymerase Chain Reaction at the mRNA Level in Tissue-Specific GHR-/- Mice
Growth Hormone (GH) inhibits insulin action, and high level GH can result insulin resistance and diabetes in both mice and humans. GH receptor (GHR) gene disrupted mice (GHR-/- mice) have been genetically modified to lack the GHR and GH action. GHR-/- mice are extremely insulin sensitive and have …
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Genexpression der GH- IGF-1 Kaskade in endokrin aktiven und endokrin inaktiven Hypophysenadenomen
… (GH) substituiert. Da GH über den Insulin-like-growth-factor-1 (IGF-1) eine mitogene Wirkung auf potentiell vorhandenes, postoperatives Tumorrestgewebe entfalten könnte, stellten wir die Frage, ob neben GH und IGF-1 auch der Growth-Hormon-Receptor (GH-R) und der IGF-1-Receptor (IGF-1-R) …
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Effects of Growth Hormone on Circulating Resistin Levels in Mice
… secreting a number of anti- and proinflammatory hormones collectively known as adipokines. With obesity, the balance shifts towards an increase in proinflammatory hormones. One such adipokine, resistin, is found to have a positive correlation with inflammation and with insulin resistance. The aim …
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Protein-Protein Interactions and Small Molecule Targeting of the Multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 Ubiquitin Ligase
… structures in complex with substrate peptides of growth hormone receptor (GHR) and erythropoietin receptor (EpoR) were solved by X-ray crystallography with a goal to elucidate the SOCS2 recognition mechanism. Different interactions of the peptides were observed in the structures as a consequence …