Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Group II metabotropic glutamate receptor"”.
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Role of Medial Prefrontal Cortical Group II Metabotropic Glutamate Receptor in the Development of Cocaine Sensitization
… the role of medial prefrontal cortical (mPFC) group II metabotropic glutamate receptors (mGluR<sub>2/3</sub>) in the development of cocaine sensitization. Initial studies demonstrated that intra-mPFC injection of the mGluR<sub>2/3</sub> receptor agonist, APDC, dose-dependently reduced acute …
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Role of group II metabotropic glutamate receptor subtype 2 (mGluR2) in appetitive and consummatory aspects of ethanol reinforcement
<p>Background: Group II metabotropic glutamate receptors (mGluR2/3) are predominately presynaptically located G<sub>i/o</sub> coupled receptors that are highly expressed in the cortex, nucleus accumbens, amygdala, and hippocampus. Previous studies suggest that group II mGluRs are involved in …
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THE GROUP II METABOTROPIC GLUTAMATE AGONIST, LY379268, DECREASES METHAMPHETAMINE SELF-ADMINISTRATION IN RATS
… for which there is no effective pharmacotherapy. Group II metabotropic glutamate receptor (mGluR) agonists are proposed to serve as an addiction treatment and have been shown to reduce the reinforcing properties of cocaine, but their efficacy has yet to be tested in METH. …
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Cellular Effects of Cerebral Ischaemia In Vitro’. Cerebroprotective Actions of GABAmimetic agents
… that during an ischaemic insult extracellular glutamate levels dramatically increase and this increase is strongly implicated in neuronal death. Decreased function of inhibitory mechanisms may also contribute to ischaemia-induced cell death. The mechanisms involved in ischaemia-induced …