Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Group I metabotropic glutamate receptor"”.
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GROUP I METABOTROPIC GLUTAMATE RECEPTORS ON SELECTIVE CELLULAR SUBTYPES IN EPILEPTOGENIC MALFORMED CORTEX
… model indicated an increased response to group I metabotropic glutamate receptor agonists in the region adjacent to the malformation (PMZ). In addition there was a novel response in low threshold spiking (LTS) interneurons via mGluR5 activation. To determine whether cell specific …
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The role of amygdala group I mGluRs in synaptic plasticity and conditioned place preference in rodents
… is not available. Previous studies found that group I metabotropic glutamate receptor (mGluR) antagonists can block the induction of conditioned place preference (CPP), a measure of cocaine seeking behavior, but their functions after clinically relevant withdrawal periods are not known. Our …
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Direct neuronal and microglia-mediated effects of group I metabotropic glutamate receptors in neurodegenerative and neuroinflammatory processes
The group I of metabotropic glutamate (mGlu) receptor, mGlu1 and mGlu5 receptors are involved in neurodegenerative and in neuro-inflammatory processes. We have examined the role of mGlu5 receptor in a neuroinflammatory context. This receptor is expressed in glial cells and has been reported to play …
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Modulation of Stress Granules formation: Role of mGlu5 receptor and FMRP and implications for pathophysiology of Fragile X Syndrome
… FXS symptoms are a consequence of a defect in group-I metabotropic glutamate receptor, namely mGlu5; pharmacological blockade of mGlu5 receptors provide a therapeutic target in FXS. mGlu5 receptor, like FMRP, regulates protein synthesis but in a functionally opponent manner: mGlu5 receptor …