Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Graves´ disease"”.
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Molecular Etiology of Graves’ Disease and Associated Ophthalmopathy
Graves' disease (GD) is a complex autoimmune disorder characterized by hyperthyroidism and diffuse goitre. 25-50% of the patients with GD develop eye symptoms, Graves' ophthalmopathy (GO). The overall aim of this thesis was to explore the molecular etiology of GD and GO. By studying gene expression …
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The evolution of the autoantibody response in Graves’ disease
Graves’ disease (GD) is an antibody-mediated autoimmune disease caused by thyroid stimulating antibodies (TSAbs) activating the thyrotropin receptor (TSHR). Both genetic and environmental factors contribute to pathogenesis and one such factor is the infectious agent, Yersinia enterocolitica. Two …
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A descriptive analysis of children and adolescents with Graves disease attending the paediatric endocrinology services of the Red Cross War Memorial Children's Hospital and Groote Schuur Hospital over 20 years
… in about 1 per 5000 children and adolescents. Graves disease (GD) is the most common cause of hyperthyroidism in children and adolescents. The treatments that are currently available for children with GD include Carbimazole (CMZ), radioactive iodine (RAI) therapy and surgery. The paucity of GD …
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The role of the HLA region in Hashimoto’s Thyroiditis
Hashimoto’s Thyroiditis is an autoimmune disease of the thyroid gland characterised by thyrocyte death. Although it was previously thought that Hashimoto’s thyroiditis shared common aetiology with Graves’ disease, there is now significant evidence to suggest separate causal loci. The aims of this …
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The Life Story Analysis of Those Suffering from Autoimmune Thyroiditis
… thyroiditis, specifically Hashimoto’s and Graves’ disease. To accomplish this, the life story methodology was utilized to gather individual experiences from 11 participants diagnosed with Hashimoto’s or Graves’ disease. The participants completed a background and general health …
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Clinical problems in thyroid surgery
… considered the method of choice when treating Graves´ disease (GD) and multinodular goitres (MNG) surgically. Hypocalcaemia is the most common adverse event after thyroid surgery and the reported frequency ranges from 4-55 %. It is difficult to identify and predict patients at risk for …
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Avaliação da superfície ocular em pacientes com doença ocular da tireoide
Introduction: Thyroid eye disease (TED) is the most common and severe extrathyroidal manifestation in patients with Graves' disease, affecting 25-50% of these patients. Ocular surface disease (OSD) is a multifactorial disorder characterised by an imbalance in tear film homeostasis, resulting from …
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Einfluss der thyreostatischen Therapie auf den Erfolg einer Radioiod-Ersttherapie bei der Autoimmunthyreopathie vom Typ M. Basedow
Ziel vorliegender Studie war die Einflussfaktoren der Radioiodtherapie bei der Autoimmunthyreopathie vom Typ M. Basedow insbesondere im Hinblick auf die prätherapeutische thyreostatische Therapie aufgrund der unklaren Datenlage zu erfassen. Der Einfluss von Geschlecht, Alter, Schilddrüsenvolumen, …
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Orale versus intravenöse Radioiodtherapie bei Unifokaler Autonomie und Morbus Basedow
Im Rahmen der dieser Arbeit zugrunde liegenden prospektiven, randomisierten Studie wurden im Zeitraum Juli 2001 bis August 2002 insgesamt 120 Patienten der Klinik und Poliklinik für Nuklearmedizin der Universität Würzburg mit den Diagnosen Unifokale Autonomie (UFA) und Morbus Basedow (MB) mit einer …