Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 542 for “"Gram-positive"”.
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On the Gram-positive bacterial cell wall.
Cell wall is the outermost part of Gram-positive bacteria. It is intricately tied to the bacteria's response to environmental stimuli and challenges, and its makeup dynamically changes as a part of bacterial adaptation. Peptidoglycan is the biopolymer that composes nearly half of the cell wall, and …
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Oxidative Protein Folding Pathways In Gram-Positive Actinobacteria
… like the eukaryotic endoplasmic reticulum and Gram-negative bacterial periplasm. Protein oxidation has been well-studied in these organisms, but largely ignored in Gram-positive bacteria. Due to the absence of an outer membrane, these organisms are thought to lack compartments in which to …
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Biosynthetic and Functional Studies of Bacillithiol in Gram-positive Bacteria
… LMW thiol in eukaryotic cells as well as Gram-negative bacteria and mycothiol (MSH) as the dominant LMW thiol in Actinobacteria. Functional studies on those thiols have revealed their importance in cell metabolism, also their potential as target for antimicrobial development. …
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Biological Consequences of Atypical Phage Conversion in Gram-Positive Pathogens
<p>Temperate bacteriophage have a complex, dynamic relationship with bacteria: parasitizing in the lytic cycle, but often increasing bacteria's fitness as lysogens. The phage-bacteria relationship is vast and has evolved over more than an estimated three billion years, and there are likely many …
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Gram-positive infections in patients with end-stage renal disease
Gram-positive microorganisms, specifically coagulase-negative staphylococci are the most common species recovered from clinical culture specimens of patients with end-stage renal disease. The propensity of coagulase-negative staphylococci (CNS) to cause infection in this patient group has been …
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Regulation of Surface Proteins Assembly on the Wall of Gram-Positive Bacteria
… proteins are essential virulence factors in many Gram-positive bacteria. Attachment of these proteins to the peptidoglycan is achieved through a transpeptidation reaction, whereby sortase cleaves a conserved Cterminal LPXTG motif and attaches the protein to the peptidoglycan precursor lipid II. …
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Xenophagy in response to gram-positive staphylococcus aureus and gram-negative salmonella enterica sv. typhimurium
Autophagy is an important process for cell survival in the human body, which plays a critical role in fighting infections. Some infections exploit the autophagic system and are often promoted by autophagy. Recent evidence has suggested that Staphylococcus aureus has specialised mechanisms to evade …
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Antibodies to peptidoglycan differentiate between cell wall fragments of gram-negative and gram-positive bacteria
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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An investigation into the biodegradation of peptide cyanotoxins (microcystins and nodularin) by novel gram-positive bacteria.
Cyanobacterial secondary metabolites, microcystins (MC) and nodularin (NOD) have become common contaminants in most aquatic ecosystems over recent years presenting a hazard to animal and human health. Unfortunately, these chemically diverse peptide hepatotoxins remain a challenge to most …
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A study of potential serum markers for a diagnosis of gram-positive and gram-negative bacterial sepsis
… of clinically diagnosed patients with eithera Gram-negative or Gram- positive bacterial sepsis for elevated levels of nine potentialmarkers of sepsis, using commercially produced enzyme linked immunosorbent assays(ELISA). The purpose was to find a test marker for sepsis that would be helpful …
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The development of a flagellin surface display expression system in the gram-positive bacterium, Bacillus halodurans Alk36
… development of an alkaliphilic, thermo-tolerant, Gram-positive isolate, Bacillus halodurans Alk36, for the over-production and surface display of chimeric gene products. This bacterium harbors the endogenous genetic background to over-produce flagellin protein continuously. In order to harness …
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Determining the mechanism of protein transit through the peptidoglycan layer in Gram-positive bacteria and identifying phage-docking sites on Clostridium perfringens
Clostridium perfringens is a Gram-positive (Gram+) anaerobic spore-forming bacterium that can act as a lethal human pathogen. Depending on the pathway of entry and strain, infection can lead to gastrointestinal disease or gas gangrene. Disease, as with nearly all bacterial pathogens, is primarily …
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A controlled in vitro study of the effectiveness of Alepidea amatymbica herbal tincture and homoeopathic dilutions (01 and 06) against Gram-positive and Gram-negative bacteria
Mini-dissertation submitted in partial compliance with the requirements for the Master's Degree in Technology: Homoeopathy, Durban Institute of Technology, Durban, South Africa, 2003.
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A controlled in vitro study of the effectiveness of Withania somnifera herbal tincture and homoeopathic dilution (1X and 6X) against selected gram-positive and gram-negative bacteria
Mini-dissertation submitted in partial compliance with the requirements of the Master's Degree in Technology: Homoeopathy, Durban Institute of Technology, Durban, South Africa, 2003.
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Assessment of dairy product quality by selective incubation and rapid techniques
… evaluated for their ability to allow growth of gram-negative psychrotrophic bacteria while inhibiting growth of gram-positive organisms. Crystal violet, benzalkonium chloride, a mixture of crystal violet and benzalkonium chloride, and alkylaryl sulfonate were tested. These were incubated with …
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A study of the phylogenetics, nutrition and one-carbon metabolism of Syntrophococcus sucromutans
… sucromutans is phylogenetically included in the Gram-positive phylum of the Eubacteria, by virtues of 16S ribosomal RNA sequence similarity analysis. It is part of a well defined genealogic entity described as the Butyrivibrio subdivision which, like the Sporomusa subdivision contains both …
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Development of novel compounds to improve the resistance profile and spectrum of activity of fusidic acid
… as no new classes of antibiotics that target Gram-negative bacteria have been approved by the Food and Drug Administration (FDA) since the introduction of the fluoroquinolones in 1968. While seven new classes of Gram-positive-only antibiotics have been introduced to the market since 1968, the …
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Transition Metal Complexes of Novel Phenanthroline Derivatives and their Antibacterial Activity
… and its metal complexes were studied using a Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria and a fungal (Candida albicans) strain. In addition, lipophilic derivatives of the oxazine-based phen derivatives and its Cu(II) complexes were also prepared, …
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Identification and functional characterisation of an antimicrobial peptide QUB-1529 from the skin secretion of the Asian frog, Hylarana guentheri
… an excellent antibacterial activity against the Gram-positive bacterium, S. aureus, and the yeast, C. albicans.<br/><br/>With the rapid rise in antibiotic drug resistance, traditional antibiotics have become increasingly irrelevant in clinical practice despite increasing demand. The discovery of …
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