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Showing 1 to 1 of 1 for “"Gram-negative accumulation"”.
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The influence of positively charged nitrogen species on compound accumulation and activity in gram-negative bacteria
Multidrug resistant Gram-negative bacterial infections are on the rise, and with no FDA approvals for new classes of broad-spectrum antibiotics in over 50 years, these infections constitute a major threat to human health. A significant challenge is the inability of most compounds to accumulate in …