Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Golgin"”.
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The function of golgin vesicle tethers in Drosophila melanogaster
… sorting hub of membrane traffic in the cell. Golgins, a class of highly conserved coiled-coil vesicle tethers, have been shown to mediate specificity of membrane traffic to the Golgi via the mitochondrial relocation assay in mammalian tissue culture cells (Wong and Munro, 2014). However, …
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Characterization of Novel Neuronal Antigens in the Central Nervous System of Manduca Sexta
The predicted amino acid sequence of Ms-golgin80 is similar to several members of a growing family of coiled-coil, Golgi-associated proteins, including GM-130 and golgin-95. The Drosophila and Caenorhabditis elegans homologs of Ms-golgin80 were also identified through homology sequence search. …
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Investigating the trafficking of Golgi-resident glycosylation enzymes
… proteomic screen was applied to the intra-Golgi golgin tethers GMAP-210 and golgin-84 to identify novel intra-Golgi vesicle-resident factors. The screen identified the Rab2 effector of unknown function FAM114A2. FAM114A2 and paralogous protein FAM114A1 were shown to specifically associate with …
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Investigation of conventional and unconventional protein secretion using galectin-3
… on Golgi morphology by its interaction with golgin A5. This thesis presents new insights into both conventional and unconventional protein secretion. Insights into the mechanism for galectin-3 secretion were revealed. A novel Golgi-localised regulator of secretion, GRP161, was identified, …
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The role of Atgolgin-84A at the plant ER-Golgi interface
… bodies, and Golgi matrix components, such as golgins, have been identified and suggested to function as putative tethering factors. Golgins are proteins anchored to the Golgi membrane by the C-terminus either through transmembrane domains (TMDs) or interaction with small regulatory GTPases. …