Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Golgi traffic"”.
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DISSECTING THE ROLE OF GOLGI TRAFFIC IN BRAIN DEVELOPMENT ACROSS HEALTH AND DISEASE: A LESSON FROM COG5-CDG STUDIES
… and intracellular architecture. Interestingly, Golgi apparatus (GA) is differentially positioned in APs and BPs. GA is the main hub for glycosylation and defects in GA and associated glycosylation are observed in a group of rare multi system diseases collectively referred to as Congenital …
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Vps1, a Novel Recycling Factor For the Traffic of Early Endosome to Late Golgi
… In the budding yeast, there are recycling traffics from early and late endosomal compartments to the late Golgi. Here, I examined a possible role for Vps1, a large GTPase, in the recycling traffic of GFP-Snc1 from early endosomes to the late Golgi. In the absence of Vps1, I observed an …
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Structure/Function Studies on Vps9 domain-containing Ankyrin Repeat protein (VARP)
… has more recently been proposed to bind to the Golgi tether golginA4, the kinesin motor Kif5a and the retromer complex subunit Vps29. The retromer core complex, comprising Vps35, Vps26, and Vps29, utilises different SNX proteins to mediate both Endosome to Golgi traffic, and Endosome to Plasma …
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Investigating the trafficking of Golgi-resident glycosylation enzymes
The Golgi is a major site of glycan processing mediated by a large number of Golgi-resident glycosylation enzymes. These enzymes are largely type II transmembrane domain (TMD) proteins consisting of a short N-terminal cytosolic tail, a short TMD and a lumenal ‘stem’ region which separates the …
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Characterising the factors involved in ER-to-Golgi anterograde trafficking
The Golgi apparatus is a major hub of protein transport, modification and sorting. Secreted and membrane proteins are synthesised in the Endoplasmic Reticulum (ER) and are packaged into carrier vesicles at ER exit sites. The carriers are transported to the cis-Golgi apparatus, where they fuse with …
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The Arf GTPase exchange factor Sec7p interaction network:
The Golgi apparatus is the main crossroad of the intracellular trafficking network in all eukaryotic cells and plays a crucial role in the distribution of cellular material. To ensure the proper sorting and delivery of cargo proteins to their destination while maintaining Golgi homeostasis the …