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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Gnrh-a"”.
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IDENTIFICATION OF MECHANISMS OF DELAYED PUBERTY ON BONE STRENGTH DEFICITS DURING DEVELOPMENT
… with gonadatropin releasing hormone antagonists (GnRH-a) and energy restriction (30%). Thirty-two female Sprague Dawley rats (21 to 22 days-of-age) were received from (Charles Rivers Laboratories, Wilmington, MA, USA) and housed individually at the Temple University Central Animal Facility (Temple …
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Factors involved in the control of plasma thyroid hormone concentrations during an induced molt in the domestic hen
… of a gonadotropin releasing hormone agonist (GnRH-A; (D-Leu$\sp6$,Pro$\sp9$) -GnRH N-ethylamide), and compared with molt induced by FW. Hens were divided into three groups: (1) sham infused (controls); (2) molted by GnRH-A infusion (GnRH-A); or (3) molted by FW. Plasma was assayed for T$\sb4$, …
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The cloning of novel gonadotropin-releasing hormone receptors by polymerase chain reaction
Gonadotropin-releasing hormone (GnRH), a central regulator of reproductive function in all vertebrates, exerts its effects via binding to the GnRH receptor (GnRHR) in the pituitary gonadotrophs. The GnRHR is a member of the G-protein coupled receptor (GPCR) superfarnily. A second form of the GnRHR …
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Generation of a FHV-1 Viral Vaccine Against Gonadotropin Releasing Hormone for Immunocontraception of Felines
… (EGFP), and Gonadotropin Releasing Hormone (GnRH). FliC has been shown to stimulate a heightened antibody response when antigens are expressed as fusion proteins with it. GnRH, a major reproductive hormone responsible for the development of testes and ovaries in felines, is the target of our …
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On the neuroendocrine regulation of reproduction: Functional characterization and kinetic studies of the lamprey gonadotropin -releasing hormone receptor and cloning and analysis of the cDNA encoding lamprey gonadotropin-releasing hormone-III
… is regulated by gonadotropin-releasing hormone (GnRH), a decapeptide that is produced and released from the hypothalamus. At the anterior pituitary, GnRH action is mediated through high affinity binding with the GnRH receptor, a rhodopsin-like seven transmembrane G-protein coupled receptor …
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New stimulators and a new mechanism of regulated secretion in pituitary gonadotropes
… is the peptide gonadotropin-releasing hormone (GnRH). It acts via a rise in intracellular Ca$\sp{2+}$ concentration ( (Ca$\sp{2+}\rbrack\sb{\rm i}$). I used cultured pituitary gonadotropes of male rats to seek other possible agents and mechanisms that might regulate gonadotropin secretion. The …
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Characterization of AG10, a potent stabilizer of transthyretin, and its application in enhancing in vivo half-life of therapeutic peptides
… a model peptide Gonadotropin Releasing Hormone (GnRH) and its analog GnRH-A without compromising their potency. Apart from GnRH, we have used other peptides to study their proteolytic stability in vitro . Our approach involves endowing peptides with a small molecule that binds reversibly to the …
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NOVEL INSIGHTS INTO GENETIC AND ENVIRONMENTAL DETERMINANTS SHAPING GNRH NEURON BIOLOGY AND RELATED REPRODUCTIVE DISORDERS
… the secretion of gonadotropin-releasing hormone (GnRH), a neuropeptide that stimulates the release of gonadotropins from the pituitary, driving gametogenesis and sex steroid production. GnRH-secreting neurons originate from the olfactory placode during embryogenesis and migrate into the forebrain …