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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 118 for “"Glycosides"”.
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Asymmetric syntheses of anthraquinonyl C-glycosides
Syntheses of C2-anthraquinone aldehydes from the commercially available anthrarufin 11 have been investigated. A synthesis of the ketoaldehyde 5 in nine steps and 73% overall yield was achieved. Syntheses of 5 exploiting selective oxidations of either a C-bound allyl group via Wacker oxidation to …
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Site-selective C-H Bond Diversification of Glycosides
Synthetic carbohydrates have recently emerged as an important motif in the development of modern therapeutics. Despite the biological significance of carbohydrate mimetics, synthetic challenges continue to limit the widespread implementation of these compounds. The thesis presented herein includes …
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Removal of Cyanogenic Glycosides in Whole Flaxseed via Lactobacillaceae Fermentation
… foods. However, flaxseed contains cyanogenic glycosides (CGs), including linamarin, linustatin, lotaustralin and neolinustatin. Cyanogenic glycosides are metabolized to cyanohydrins by the action of the enzymes beta-glucosidase and hydroxynitrile lyase which first cleave glucose from CG then …
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Effect of vineyard management of Cabernet Sauvignon (Vitis vinifera L.) grape glycosides
Quantification of grape glycosides has been suggested as an objective index of grape quality. Two studies were undertaken to observe the influence of vineyard management on grape glycosides. In the first study, three crop levels from mature Cabernet Sauvignon (<i>Vitis vinifera</i> L.) vines grown …
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BIOSYNTHESIS AND FUNCTION OF CARDIAC GLYCOSIDES IN THE CRUCIFER GENUS <i>ERYSIMUM</i>
… a different group toxic compounds called cardiac glycosides or cardenolides. Cardiac glycosides have been used to treat heart conditions for hundreds of years and are on the World Health Organization's list of essential medicines. However, the biosynthetic pathway remains unknown. In Chapter 1 of …
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Substituted aryl glycosides as probes of the mechanism of spontaneous ad enzyme-catalyzed glycoside hydrolysis
… 2',4'-dinitrophenyl P-D-glycopyranosides (DNP glycosides) was synthesized and used to probe the mechanisms of spontaneous and enzyme-catalyzed hydrolysis of 0-glycosides. The relative rates of spontaneous hydrolysis of the DNP glucosides followed the trend 4-deoxy > 3-deoxy - 6-deoxy > parent > …
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A study of Glycosides in grapes and wines of Vitis vinifera cv. Shiraz / Patrick George Iland.
Studies the links between grape composition, wine composition and wine sensory properties. Developed a new method of measuring glycoside concentration in grapes (glycosyl-glucose assay) and a modified measurement of wine colour density in red wine. These were used to analyse samples of Shiraz …
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Effect of Training Systems on Viognier (Vitis vinifera L.) Grape and Wine Glycosides and Volatile Compounds
… and evaluated for the effects on grape and wine glycosides and volatile compounds. Fruit was harvested at the same Brix each season, and differences in berry weights were not observed. VSP-trained vines had the lowest crop load and lowest light levels in the fruit zone. Seventeen volatile …
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The Development of a Per-O-Benzylated 1-C-Aryl-glycal for the Synthesis of Kdo Glycosides
… be a versatile donor for the synthesis beta-Kdo glycosides. The glycosylation was accomplished with high regio- and stero- selectivities by using N-iodosuccinimide (NIS). It was postulated that the reason for the observed beta-glycosylyation results arose from the presence of a fused …
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The Synthesis of Functionalized Glycosides: Coordination Chemistry, Antiparasitic Activity, Precursors to Conformationally Constrained Macrocyclic Architectures and Photophysical Properties
… thesis focuses on the synthesis of functional glycosides and the investigation of their properties. This included the study of their ability to form metal complexes and the study of the antiparasitic activity of both the free glycosides and metal complexes, the use of glycosides to serve as …
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The effects of different processing parameters (cold soak and percent alcohol (v/v) at dejuicing) on the concentrations of grape glycosides and glycoside fractions and glycosidase activities in selected yeast and lactic acid bacteria
… exist partially as non-volatile, sugar-bound glycosides. Hydrolysis of these compounds may modify sensory attributes and potentially enhance wine quality. Cold soak (prefermentation skin contact) at two temperatures and alcohol content (%, v/v) at dejuicing were monitored to determine effects …
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The effects of post-fermentation and post-bottling heat treatment on Cabernet Sauvignon (V. vinifera L.) glycosides and quantification of glycosidase activities in selected strains of Brettanomyces bruxellensis and Oenococcus oeni
… for 21 days) to determine the effects on total glycosides and glycosidic fractions. Total and phenol-free glycosidic concentrations in the wine and skins were quantified by analysis of glycosyl-glucose. Pre-dejuicing thermal vinification resulted in higher total glycosides (12%), phenol-free …
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I. Sulfonium-Mediated Oxidative Glycosylation of Glycal Donors for the Synthesis of C(2)-Hydroxy-Beta-Glycosides. II. Hypervalent Iodine (iii)-Mediated Oxidative Glycosylation of Glycal Donors for the Synthesis of C(2)-Acyloxy-Beta-Glycosides. III. Efforts Toward the Synthesis of Immunologic Adjuvant Qs-21a(api)
Development of two novel glycosylation procedures, and the synthesis of immunologic adjuvant QS-21Aapi is reported. In the first glycosylation procedure, glycals were employed as glycosyl donors and activated with a reagent combination of diphenyl sulfoxide and triflic anhydride. This …
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Evaluation of the antioxidant activity of extracts and flavonol glycosides isolated from the seed coats of coloured beans (Phaseolus vulgaris L.)
… food and nutraceutical industry. Flavonol glycosides were identified from acetone extracts of seed coats of black beans, pinto beans, and dark and light red kidney beans, representing nine varieties grown in Manitoba. Based on HPLC-MS/MS, black beans contained the 3-O-glycosides of …
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Cyclopentenoid Cyanogens: Their Chemistry, Importance in Plant Systematics, and Their Role in the Coevolution of Plants and Insects (Phytochemistry, Cyanogenic, Glycosides, Nmr)
Cyanogenic glycosides containing a cyclopentene ring were investigated chemically. Techniques for their isolation from plant sources were devised, and data accumulated on their spectroscopic properties. The distribution of cyclopentenoid cyanogens in plants was investigated, and it was determined …
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Synthesis and reactions of benzyl 2-bromo-2-deoxy hexoses
… can be used for the synthesis of 2-halo benzyl glycosides. And these derivatives can be used to synthesize biologically interesting compounds which were not previously attainable using the 2-halo-2-deoxy methyl glycosides which are currently available.
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The effects of vineyard management and primary and secondary fermentations on grape glycoconjugates and conjugate fractions
… exist partially as non-volatile, sugar-bound glycosides. Hydrolysis of these compounds may modify sensory attributes and potentially enhance wine quality. In the first study, four levels of shoot thinning (control, 20, 25, and 30 shoots per meter) with and without basal leaf removal (2-4 …
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Brønsted acid-catalyzed stereoselective allylation of exo-glycals with allyltrimethylsilane
… compounds. However, the preparation of C,C-glycosides is a challenge, and to date, many studies have failed to exploit exo-glycals as starting materials. The allylation methodologies of sugar lactol and sugar lactone starting materials suffer from poor regio- and stereoselectivity. Recently, …
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