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Showing 1 to 3 of 3 for “"Glycosidase inhibitors"”.
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Synthesis of Bulky and Polar Galactonoamidines for the Inhibition of the Human α-Galactosidase
<p>Glycosidases are amongst the most abundant enzymes in nature. This is due to their role in the degradation of carbohydrates which are the major source of carbon or earth. The absence or malfunction of glycosidases is implicated in numerous diseases such as cancers, diabetes, and lysosomal …
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ΣΥΓΚΡΙΤΙΚΗ ΜΕΛΕΤΗ ΤΗΣ ΓΛΥΚΟΖΟΑΙΜΟΣΦΑΙΡΙΝΗΣ (CT- 6) ΚΑΙ ΤΗΣ ΚΑΜΠΥΛΗΣ ΓΛΥΚΟΖΗΣ (OGTT) ΣΕ ΦΥΣΙΟΛΟΓΙΚΕΣ ΚΑΙ ΠΑΘΟΛΟΓΙΚΕΣ ΚΑΤΑΣΤΑΣΕΙΣ
… values were observed after administration of a-glycosidase inhibitors, for a period of three weeks to 17 diabetics patients. Highly significant was the correlation of G-Hb and OGTT at the peak of the curve (r= + 0,83) up to the extend that glucose tolerance test may be replaced by G-Hb which has …
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Human testis angiotensin-converting enzyme: crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis
… via mutation, rather than using expensive glycosidase inhibitors, iii should prove advantageous for further structural studies, such as the study of the binding of novel inhibitors. In all of the tACE structures thus far observed, the active site is closed off from the external medium in a …