Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 620 for “"Glycoprotein"”.
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Invertebrate glycoprotein-induced inflammation in rats
The present program of research, therefore, was designed to attempt to gain new insights into the possible etiology of inflammatory states - for when new information concerning the etiology of these diseases states becomes available, more meaningful screening procedures for anti-inflammatory drugs …
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High-throughput quantification of glycoprotein sialylation
Sialic acid can improve qualities of therapeutic glycoproteins, such as circulatory half-life, biological activity, and solubility. In production of therapeutic glycoproteins, a high-throughput method (HTM) is required for process monitoring and optimization to ensure consistent and optimal sialic …
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The Nuclear Pore Complex: Novel Glycoprotein Constituents
… In fact, it is a member of a family of novel glycoproteins that are labelled in vitro when nuclei are incubated with UDP-<sup>3</sup>H-galactose in the presence of galactosyl transferase. These proteins have been shown to contain O-linked monosaccharidic GlcNAc residues (Holt, G.D. and G.W. …
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Rh Glycoprotein as an Ammonia Transport Molecule
… by one or more transport proteins in the Rh glycoprotein (RhxG) family. Longhorn sculpin (Myoxocephalus octodecemspinosus) cDNA was amplified using polymerase chain reaction (PCR) and then the PCR products were visualized on an agarose gel. The cDNA from the gel bands was then sequenced and …
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Platelet Receptor Glycoprotein VI in Ischaemic Stroke
… it is established that platelet surface receptor glycoprotein (GP) VI-dimer binds to exposed sub-endothelial collagen, initiating the signalling required to cause platelet activation. Then, separate platelet-fibrin interactions cause the thrombus to grow, culminating in distal tissue ischaemia; …
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Protein dissection of the Ebola virus glycoprotein
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
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Investigating the pathway of asparagine-linked glycoprotein biosynthesis
The biosynthesis of asparagine-linked glycoproteins, highly conserved throughout all eukaryotes, requires a dolichylpyrophosphate-linked tetradecasaccharide precursor (Dol-PP-GlcNAc2Man9Glc3), from which the tetradecasaccharide is transferred co-translationally to nascent polypeptides in the lumen …
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ANTIMICROBIAL ACTIVITIES OF HISTIDINE-RICH GLYCOPROTEIN AND CATIONIC PEPTIDES
… from domain 5 of kininogen and histidine-rich glycoprotein (HRGP). HRGP, an abundant heparin-binding plasma protein, exerted antimicrobial effects against Gram-positive and Gram-negative bacteria and fungi. The antibacterial activity of HRGP was dependent on Zn2+-ions or low pH, and the …
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Regulation of P-glycoprotein at the Blood-Brain Barrier
… function is the ATP-driven efflux transporter, P-glycoprotein (P-gp) that denies CNS entry to a myriad of therapeutics. Thus, a better understanding of the mechanisms regulating P-gp expression and transport function might provide new strategies to improve drug delivery to the brain and increase …
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Elucidation of antigenic epitopes on the rubella virus E1 glycoprotein
… a host derived lipid bilayer membrane, membrane glycoprotein spikes, and the C protein which together with viral RNA forms the icosahedral nucleocapsid. Although clinical rubella is a relatively mild disease, RV remains an important human pathogen because of its teratogenic effects in utero which …
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The regulation and role of glycoprotein C during herpesvirus pathogenesis
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Solid-state NMR investigation of viral fusion glycoprotein 41 (gp41)
… processes and viral entry. The HIV envelope glycoprotein mediates viral entry into target cells by fusing the viral envelope with the cell membrane. This process requires large-scale and multi-step conformational changes of the viral fusion protein gp41. Our current understanding of the …
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Placental P-glycoprotein: Role in disposition of medications administered during pregnancy
… activity of the placental efflux transporter P-glycoprotein (P-gp) and its role in regulating the placental distribution of medications used during pregnancy. P-gp expression and transport activity were defined in brush border membrane vesicles prepared from human placenta of various gestational …
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