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Showing 1 to 5 of 5 for “"Glycopolymer"”.
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Surface Modification of Spherical Particles with Bioactive Glycopolymers
Glycopolymers containing different kinds of carbohydrates were grafted from various spherical templates, whereby the glycopolymer chains were prepared via controlled radical polymerization techniques, namely ATRP and RAFT. A library of carbohydrate-displaying spheres and their interaction with …
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Design, Synthesis, and Characterization of Glycodendrons Through Small Molecule and Linear Polymer Models
… the design, synthesis, and characterization of glycopolymer-dendron thiol-ene coupling reactions with the long-term goal of increasing biocompatibility of near infrared (NIR) fluorophores for bioimaging applications. A design of experiments was used with small molecule model compounds to …
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Glycan polymeric prodrugs against pulmonary intracellular alveolar infections
… techniques to explore synthetic multivalent glycopolymer prodrug systems. Prodrugs are inactive forms of the drug, but when administered undergo hydrolysis to release the pharmacologically active drug. We hypothesized that engineering mannose glycopolymer prodrugs to target the macrophage …
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SYNTHESIS AND CHARACTERISATION OF NOVEL BIOPOLYMERS VIA CLICK CHEMISTRY
… of Click chemistry to produce trehalose-based glycopolymers which have a wide range of potential applications. Biodegradable glycopolymers containing PCL or PLA were synthesised via combination of ring opening polymerisation (ROP) and Click chemistry. The ROP of lactide and ε-caprolactone, …
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Complexation Between DNA and Hydrophilic-Cationic Diblock Copolymers
DNA-polycation complexes (polyplexes) are gene delivery vehicles that offer a number of advantages over viral vehicles: high genetic payload capacity, low toxicity, and low cost. Among the many polycation architectures, hydrophilic-cationic diblock copolymers are particularly promising due to their …