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Showing 1 to 20 of 47 for “"Glycero"”.
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1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine (Platelet Activating Factor): Interactions with Sheep Platelets
<p>Platelet Activating Factor (PAF) seems to link platelet function with allergy and inflammation. Early events associated with the action of PAF on platelets are poorly understood, but PAF appears to interact with a platelet membrane receptor. Two photoaffinity-labelling analogs of PAF, …
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Identification and imaging different lipid species within phase-separated model membranes by integration of TOF-SIMS and principal component analysis
… phosphatidylcholine species, 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), according to variations in the relative intensities of …
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The effects of polymer-controlled hydration on nuclear magnetic resonance parameters
… were composed of either 1, 2-dimyristoyl-sn-glycero-3-phophocholine (DMPC) or 1, 2-dipalmitoyl-sn-glycero-3-phophocholine (DPPC) and oriented between glass slides. These lipids were deuterated in the head group to allow their study with 2H Nuclear Magnetic Resonance (NMR). Specifically, the …
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Formulation of targeted drug-loaded nanoparticles for lung cancer therapy
… with varying molarratio of 1, 2-Distearoyl-sn-glycero-3-phosphocholine, 1, 2-Dipalmitoyl-sn-glycero-3-phosphocholine, 1, 2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) and cholesterol were fabricated using microfluidics technique with staggered herringbone mixer. Desired liposomal …
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Insulin based analogs HLVEALYLV and LVEALYLV to inhibit the formation of amyloid fibrils in beta cells
… using a 7:3 ratio of the lipids 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3- (phospho-L-serine) (DOPS), respectively, and the percent leakage of fluorescent dye from the vesicles in the presence of the peptides was calculated as compared to a 100% Triton-X …
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Mechanism Determination of the Effects of Pancratistatin on Model Mitochondrial Membranes
… of three lipids: 1-palmitoyl-2-oleoyl-sn- glycero-3-phosphocholine (POPC), 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE), and tetraoleoyl cardiolipin (TOCL). Small-angle neutron and X-ray scattering (SANS and SAXS) were utilized to determine how PST influences membranes …
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Understanding correlations between secondary relaxations and thermal behaviour of biologically relevant molecules
… phosphatidylcholines: 1,2-dilauryl-sn-glycero-3-phosphocholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) with acyl chain lengths of 12, 14, 16 and 18, respectively …
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NMR characterization of chlorhexidine in lipid-based formulations /
A mixture of Chlorhexidine digluconate (CHG) with glycerophospholipid 1,2-dimyristoyl- <^54-glycero-3-phospocholine (DMPC-rf54) was analysed using ^H nuclear magnetic resonance. To analyze powder spectra, the de-Pake-ing technique was used. The method is able to extract simultaneously both the …
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Surface Functionalisation of Metal-Organic Frameworks for Biomedical Applications
… three different phospholipids—1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)—to enhance its internalisation in cancer cells. The coated MOFs underwent a full physicochemical …
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Autoimmune Responses to Atherosclerotic Lipids: A Study In Murine Models of Atherosclerosis and Obesity
… from phospholipid 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine by oxidization, 1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine (PGPC) is v commonly found in atherosclerotic plaques. Upon stimulation with PGPC, spleen-derived CD1d-restricted T cells produced higher levels of …
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Nanostructured Organic and Inorganic Thin Films With Novel Molecular Recognition Properties
… of unilamellar vesicles of 1,2-dimyristoyl-sn-glycero-3-phosphocholine(DMPC) to mixed SAMs containing ferrocene-functionalized hexadecanethiol chains(FcCO 2C16SH). The structures were characterized by several methods, including CV, ellipsometry and surface plasmon resonance(SPR). Studies …
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Synthesis and Evaluation of Trans-bilayer Cross Linking Phospholipids Based on Click (Azide-Alkyne) Chemistry
… alkyne on the alkyl chain of sn2 position. Sn-glycero-3-phosphocholine (GPC) was used as glycerol back bone with two available hydroxyl groups for esterification. The first esterification was done using dibutyltin oxide as catalyst and palmitoyl chloride as acylating agent on the primary …
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Rate dependent rupture of solid-supported phospholipid bilayers.
… of bilayer rupture. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) solid-supported lipid bilayers were created on mica using vesicle fusion technique and then ruptured normal to the surface using a silicon nitride cantilever tip (radius#80nm). High resolution force spectroscopy was …
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Lipid catabolism in Treponema
… of phospholipid catabolism. Phospholipase B and glycerophosphorylcholine diesterase activities were demonstrated in five species of Treponema. Acid phosphatase activity was demonstrated in two species. Utilization of L-α-glycerophosphate and glycerol, products of phospholipid catabolism, was …
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Studies in synthetic carbohydrate chemistry: Part 1. Nitromethane cyclization of sugar polyaldehydes with a view to the synthesis of nitrocyclodextrins. Part 2. Approaches to the synthesis of 2-(R)-fluoro-daunosamine, a carbohydrate moiety for an antitumor drug.
… 5,7-O-benzylidene-3-deoxy-3-nitro-alpha-D- glycero-D-ido-heptoseptanoside was debenzylidenated, and the resulting nitrotetrol was acetylated. A twofold reductive dehydroacetoxylation of the nitro tetraacetate at C-2 and C-4, and concomitant deacetylation at O-5 and O-7 then resulted in a …
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SILOXANE-CONTAINING PHOSPHOLIPIDS AS POTENTIAL DRUG DELIVERY SYSTEMS
… liposomes related to 1-palmitoyl-2-oleoyl-sn-glycero-3-phospcocholine (POPC) and controlled released when using the model compound, calcein. With the siloxane-phospholipids being studied, zero-order release was observed and in some instances appeared to be independent of the pH of the release …
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Investigation of the Structure of Alkyne Self-Assembled Monolayers on Gold and the Development of Matrix-Enhanced Secondary Ion Mass Spectrometry Methods
… the limits of detection of 1,2-dipalmityl-sn-glycero-phosphocholine: DPPC) and 1,2-dipalmityl-sn-glycero-phosphoethanolamine: DPPE) were at least two orders of magnitude better. The data also show that ILs are suitable matrices for imaging SIMS. The IL matrices did not cause changes to the …
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EXPLORING THE EFFECTS OF PHYSIOLOGICAL ENVIRONMENT ON AMYLOID AGGREGATION
… composed of POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine) and POPS (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine) lipids. Beyond, membrane charge, membrane's physical organization can also affect peptide-peptide and peptide-membrane interactions. Here, we have curated the …
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The Biochemical Pathway Leading to Lpa Generation Upon Blood Coagulation
… acylmigration regioisomers of oleyl‑<em>sn</em>‑glycero‑3‑phosphocholine (LPAF) were synthesized. ATX preferred the <em>sn</em>‑<em>1</em> over the <em>sn</em>‑<em>2</em> regioisomer of LPAF. We propose the following LPA production pathway in blood: 1) Activated platelets secrete PLA<sub>1</sub>. …
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Synthesis and bio-pharmacological activity of antisense phosphatidyl-oligonucleotides
… of 1,2-O-dimyristoyl- and 1,2-O-dipalmitoyl-sn-glycero-3-O-phosphoryl-tetradeca-mers has been assessed by observing their effect on the expression of VEGF at mRNA level in human Neuroblastoma cells. Both the phosphatidyl-tetradecamers were able to inhibit the expression of VEGF mRNA with an …
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