Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Glycation Gap"”.
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Defining the molecular, genetic and transcriptomic mechanisms underlying the variation in glycation gap between individuals
… been observed and is referred to as the glycation gap (G-gap). This could be explained by the higher activity of the fructosamine-3-kinase (FN3K) deglycating enzyme in the negative G-gap group (patients with lower than predicted HbA1c for their mean glycaemia) as compared to the positive …
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Relationship of the glycation gap to diabetes and its complications, and the potential role of adipokines
… in insulin secretions and beta cell failure. Glycation is a common and spontaneous reaction of proteins or lipids becoming glycated after exposure to sugars, occurring in vivo without the controlling action of an enzyme. Deglycation is an enzyme-mediated pathway and fructoseamine-3-kinase …
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The role of a deglycating enzyme ‘fructosamine-3-kinase’ in diabetes and COPD
… haemoglobins are formed by the non-enzymatic glycation of haemoglobin molecules. This non-enzymatic glycation process has been strongly related to pathogenesis of chronic complications associated to diabetes. It was suggested that this glycation process may be moderated by an enzymatic …