Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"Glycated Haemoglobin"”.
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Serum 1, 5 Anhydroglucitol and Glycated Haemoglobin as Markers of Hyperglycemia in Type 2 Diabetes Mellitus at University Teaching Hospital, Lusaka, Zambia
… glucose and a hemoglobin-dependent biomarker, glycated hemoglobin A1c (HbA1c), a variant of hemoglobin A. However, adjuncts to these markers, such as 1,5 anhydroglucitol (1,5AG), have since been introduced as surrogate markers for diabetes. Poor glycemic control overtime leads to micro and …
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Social patterning in biomarkers of health, an analysis of health inequalities using Understanding Society: the UK Household Longitudinal Study
… grip strength, self-reported type two diabetes, glycated haemoglobin and lung function. The mediators explored are material deprivation and exposures, psychosocial stress and health behaviours. Using retrospective socio-economic position measures, consideration is paid to the timing of …
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An evaluation of factors that affect glycaemic control and its measurements in diabetes mellitus
… of the thesis discusses issues surrounding glycated haemoglobin (HbA1c) measurements in clinical practice. The thesis also examines several areas that influence glycaemic control in patients and evaluates other methods of glucose measurements including continuous glucose monitoring (CGMS), …
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The role of a deglycating enzyme ‘fructosamine-3-kinase’ in diabetes and COPD
… 415 million people worldwide have diabetes. Glycated haemoglobin (HbA1c) measurements were introduced many years ago as the gold standard tool for detecting and monitoring treatment as well as making management decisions for diabetic patients. Glycated haemoglobins are formed by the …
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The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
… glucose tolerance test, fasting blood glucose, glycated haemoglobin and self-report the prevalence of DM was determined. Bivariate and multivariate logistic regression analyses were performed to assess risk factors associated DM among TB patients. Due to significant differences between male and …
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The effectiveness of GLP-1 analogues compared to DPP-4 inhibitors for beta cell function and diabetes related complications among adults with type 2 diabetes: a systematic review and meta-analysis
… to insulin [PI/I] plasma concentration ratio) glycated haemoglobin (HbA1c), fasting and postprandial plasma glucose levels, diabetes related complications, and adverse drug events. Seven randomised controlled trials including 2661 participants were included in this review. The overall quality …
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Diabetic retinopathy among patients attending university teaching hospitals adult hospital medical clinic in Lusaka
… being used by 87 participants (40.9%). Median glycated haemoglobin level was high at 8.1%. One hundred sixty-three participants (76.5%) had normal VA and six (2.8%) were blind. The prevalence of DR in this study was 47.4%; 95% CI 40.8%-54.2% (101 participants), with 8.9% (19 participants) …
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Diabetic retinopathy among patients attending university teaching hospitals adult hospital medical clinic in Lusaka
… being used by 87 participants (40.9%). Median glycated haemoglobin level was high at 8.1%. One hundred sixty-three participants (76.5%) had normal VA and six (2.8%) were blind. The prevalence of DR in this study was 47.4%; 95% CI 40.8%-54.2% (101 participants), with 8.9% (19 participants) …
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Diabetes in children: impact of an innovative pharmaceutical care programme and links with concurrent illnesses
… received routine care. The primary outcome was glycated haemoglobin. The vitamin D work (Chapter 3) was designed as a case-control study with a matching ratio of 1:1. Chapter 4 (link of diabetes and hypothyroidism) was designed as a retrospective, longitudinal, cross-sectional study. <br/> …
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Correlates of sedentary behaviour among individuals at risk of developing type 2 diabetes mellitus in a low resource setting
… forthe determination of fasting glucose, glycated haemoglobin, and lipids. A Kruskal-Wallis or one-way ANOVA was conducted depending on the distribution of the numerical variable. A chi-squared or Fisher's exact test was conducted depending on the expected frequencies of the cells. Robust …
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Risk factors for cardiometabolic disease in the eThekwini Municipality (City of Durban), South Africa.
… Despite several potential advantages, the use of glycated haemoglobin (HbA1c) for diagnosis of diabetes is not established in SSA. Using plasma glucose measures as the reference, HbA1c ≥6.5% detected diabetes with high sensitivity and specificity. Furthermore, the association of anaemia, HIV, and …
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Monitoring glycation through the intrinsic fluorescence of biological fluorophores
… keratin fluorescence, there was no evidence that glycated keratin can be sensed through a nail clipping. Furthermore, neither our steady state or time resolved analysis exposed a correlation between any of the extracted fluorescence parameters and glycated haemoglobin (HbA1c). In conclusion, …
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The development and evaluation of a self-management package for people with diabetes at risk of chronic kidney disease
… systolic and diastolic blood pressure (BP), glycated haemoglobin (HbA1c), body mass index (BMI) and smoking status were collected at six time points, before, during and after the intervention. Outcomes in patients in the participating surgeries who did receive a pack (n=116) were compared …
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Cardiovascular Effects of Metformin on Left Ventricular Hypertrophy in Nondiabetic Patients with Coronary Artery Disease
… significant reduction of LVMI (P=0.005). The glycated haemoglobin A1C concentration and fasting insulin resistance index did not differ between study groups at the end of the study.<br/><br/>These results may suggest a potentially novel cardio-protective effect of metformin and raise the …
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The effects of a low-carbohydrate, high-fat diet on type 2 diabetic patients
… revealed no significant (p>0.05) changes in glycated haemoglobin (HbA1c), glucose and insulin in either the DiExG (HbA1c: p=0.592; 8.3% decrease, glucose: p=0.477; 11.1% decrease and insulin: p=0.367; 44.1% increase) or DietG (HbA1c: p=0.822; 0% change, glucose: p=0.108; 11.0% decrease and …
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Defining the molecular, genetic and transcriptomic mechanisms underlying the variation in glycation gap between individuals
… to be associated with raised blood pressure and glycated haemoglobin (conditions that coexist with diabetes). Future analysis based on these results will be necessary to elucidate the significant drivers of gene expression leading to the G-gap in these patients.
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Genetic and dietary determinants of Type 2 diabetes in a black South African population
… 3) the nutrient patterns associated with glycated hemoglobin and fasting glucose in a black South African population. Methods: Four types of genetic risk scores (GRS) were computed using the 66 SNPs that had been associated with T2D in the Europeans and Asians. This comprised of the GRSt …
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The impact of closed-loop insulin delivery on glucose control in children and young people with type 1 diabetes mellitus: Longer-term benefits across the paediatric age-spectrum
… struggle to meet treatment guidelines for target glycated haemoglobin levels. Closed-loop insulin delivery systems, consisting of glucose sensor, insulin pump and an algorithm automatically adjusting insulin delivery in response to real-time glucose levels, have the potential to transform diabetes …
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Screening of multi-omics biomarkers for Type 2 Diabetes Mellitus among Chinese population
… test (OGTT), fasting blood glucose (FBG) and glycated haemoglobin (HbA1c). These tests, however, provide “retrospective” markers for the diagnosis and prognosis of the disease, and therefore cannot be applied as predictive markers for from the perspectives of PPPM. A deeper understanding of …
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