Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Glyburide"”.
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Effect of berberine on in vitro metabolism of sulfonylureas: a herb-drug interactions study
… how absorption and metabolism of sulfonylureas (glyburide, gliclazide and glipizide) can be affected by the presence of berberine, a major chemical component of herbs used as anti-diabetics, and vice versa can provide valuable information on the potential herb drug interactions (HDIs). Methods: …
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Crystal Engineering of Pharmaceuticals: Modulating Physicochemical Properties of Active Ingredients by the Formation of Cocrystals
… considered are isoniazid, caffeine, nifedipine, glyburide, chlorpropamide and riboflavin. Co-formers selected are based on the suitability of functional groups for hydrogen bond formation. Co-crystal screening and preparation methods used include neat grinding (NG), liquid assisted grinding (LAG) …
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Hypoxic immunomodulation results in increased disease risk and altered behavior via non-canonical pathways
… A2A adenosine receptor were administered. After glyburide (K+ efflux antagonist) and 3,7-dimethyl-1-prop-2-ynyl-purine-2,6-dione (DMPX-A2A adenosine receptor antagonist) administration, both drugs significantly reduced the level of caspase-1 activation in the amygdala correlating with the …
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Effect of oral hypoglycaemic agents on placental ABC transporter expression and activity
… (for example glibenclamide, also known as glyburide). In the placenta a network of apical ATP-binding cassette (ABC) transporters facilitates the efflux of substances away from the fetus, thereby protecting the fetus from exposure to unwanted substances including medications such as …
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Cerebral Microcirculatory Effects of Maturation
… adults. Accordingly, our studies also define a glyburide-resistant but depolarization-sensitive relaxant component of the response to hypoxia, that appears to represent K<sub>Ca</sub> channels, which is of greater magnitude than the K<sub>ATP </sub>channel component, and plays a greater role in …
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Hypoxia-induced responses of porcine pulmonary veins.
… investigated. Penitrem A, 4AP, DPO-1, ZnCl2 and glyburide had no significant effect however TEA and BDM inhibited the hypoxic contraction. This suggested that TASK, KV1.5, BKCa and KATP do not play a role in the mechanism of hypoxic pulmonary venoconstriction however KV channels containing KV2.1 …
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Extracellular adenosine as a novel neuroimmune modulator
… of adenosine with the KATP channel blocker, glyburide, also blocked adenosine-dependent activation of caspase-1. Finally, mice i.p. injected with 50 μm adenosine displayed reduced locomotor activity and food intake and increase anxiety-like bahviors. These adenosine-dependent behaviors were …