Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 78 for “"Glutaraldehyde"”.
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Characterisation of the cross-linking and calcification associated with glutaraldehyde-treated cardic bioprostheses.
… factors associated with it. Amongst these is the glutaraldehyde pre-treatment of the valves during their manufacture. Glutaraldehyde has been used for the treatment of bioprosthetic valves for the last thirty years, as a cross-linking agent and a sterilant. Whilst it is assumed to introduce stable …
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Effect of concentration of glutaraldehyde and glyoxal on binding lysozyme to zein based films to control foodborne pathogens in tomatoes
… produce, specifically tomatoes. The study uses glutaraldehyde and glyoxal as binding agents to immobilize the enzyme on the packaging film. The effect of concentration of glutaraldehyde and glyoxal on the controlled release of the enzyme was studied. Concentrations of 0.1 and 0.2 g/g lysozyme: …
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Effects of glutaraldehyde crosslinking and chondroitin-6-sulfate upon the mechanical properties and in vivo healing response of an artificial skin
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1983.
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The Green Lane Valve: a Novel Decellularised Heart Valve
… scaffold that outperforms standard, glutaraldehyde-treated bioprosthetic valves, in vivo, remains to be developed. Methods: A systematic review and meta-analysis was undertaken of the clinical performance of decellularised heart valves implanted in either outflow tract position, …
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Evaluation of effect of extrusion process variables on mechanical properties of extruded collagen tubes and effect of post extrusion treatments
… coagulation methods and cross-linking time for a glutaraldehyde crosslinking process. Two crosslinking methods, considered in this study, are crosslinking by glutaraldehyde and EDC/NIHS. Result of these studies showed that, crosslinking with glutaraldehyde gives higher degree of crosslinking than …
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Extrusion and evaluation of degradation rate and porosity of small diameter collagen tubes
… small diameter collagen tubes crosslinked with glutaraldehyde and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) and Nhydroxysuccinimide (NHS) to evaluate physio-chemical properties. The samples were also evaluated for their surface area and porosity using mercury …
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Genipin-crosslinked electrospun collagen nanofibers
… and thus crosslinking was required. Glutaraldehyde, which is cytotoxic to cells, is currently the chemical crosslinking agent used by most research groups to stabilize collagen nanofibers. In this thesis, a novel approach, using genipin (a natural crosslinking agent), was introduced …
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Mitigation of the inflammatory response to bioprosthetic heart valve tissue through antigen-directed masking
… models. The study further demonstrated that the glutaraldehyde concentration applied to commercial heart valves is insufficient to mask the antigenicity of the tissue, therefore an method of masking antigens to mitigate the inflammatory response is needed.
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Bioprosthetic heart valves : ultrastructure and calcification
… low-temperature fixation(4°C) and high glutaraldehyde concentrations (> 1 %). Our in vivo experiments confirmed that commercially used fixation (delayed fixation, room-temperature and I ow concentrations of glutaraldehyde) with its concomitant high degree of tissue damage results in high …
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Evaluation of immobilizing horseradish peroxidase and alcohol oxidase in PVA-AWP polymer
… was lower (p < 0.05) when HRP was immobilized in glutaraldehyde. There was also no difference (p < 0.05) in enzyme leaching for UV 5, 10 and 15 minute exposure when immobilized in PVA-AWP. However, enzyme leaching was higher (p < 0.05) for HRP immobilized in glutaraldehyde. It can be concluded …
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Surface spills at unconventional oil and gas sites: a contaminant transport modeling study for the South Platte alluvial aquifer
… and a common constituent of produced water. Glutaraldehyde (biocide), polyethylene glycol (surfactant), and polyacrylamide (friction reducer) were the chemical additives considered for spills of hydraulic fracturing fluid because they represent different classes of common compounds used in …
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Virus-based 3-dimensional nanowire network copper and nickel electrodes
… In this process, virus was cross-linked using glutaraldehyde to form mechanically stable hydrogels, which were then mineralized using electroless deposition. The mineralized hydrogels were of micron-scale thickness with sub-micron pore sizes. SEM and FIB imagery provided visual confirmation of …
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Design, Fabrication and Performance Evaluation of an Impedimetric Urea Biosensor System
… urease-containing p(HEMA) hydrogel, iii) via glutaraldehyde crosslinking in the presence of albumin, iv) the direct covalent immobilization of urease to the IME, and v) solution borne urease]. Michaelis-Menten parameters KM, ZMAX and kcat revealed the following rank: PEGylated urease-Gel >> …
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Design of potential antiprotozoal daunorubicin derivatives
… in which drug was linked to the carrier by glutaraldehyde, were active. Treatment with these conjugates increased the survival time of infected mice from three days to as long as eleven days, and temporarily cleared parasites from the bloodstream of infected animals. Conjugates with other …
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Characterisation of the reaction of 1,4-phenylenebismaleimide with Ca²⁺-ATPase and elucidation of the intramolecular crosslink site
… species formed by intramolecular crosslink with glutaraldehyde. The glutaraldehyde crosslink involves the active site Lys 492 and Arg 678, in a zero distance link that overlaps with the ATP binding pocket, since it can be inhibited by nucleotides. It has been previously shown that the putative …
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Modification of soybean proteins by immobilized proteases
… trypsin immobilized on nylon pellets using the glutaraldehyde method was high when the pellets were treated with methanolic solution and 6 - 8% glutaraldehyde as well as high concentrations of soluble trypsin. Immobilized trypsin and chymotrypsin had uniform pKm and were stable at high …
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Immune Responses and Hematologic Alterations in Splenectomized Pigs Experimentally Infected With Eperythrozoon Suis: I. A Possible Animal Model for Cold Agglutinin Disease in Man
… control sera to agglutinate normal washed and glutaraldehyde-treated homologous and heterologous erythrocytes at selected temperatures and following treatment of sera with 2-mercaptoethanol.
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Morphology of Capillary Endothelia in Dog Heart Visualized by Scanning Electron Microscopy: The Effects of Ischemia and AMP
… pits. We were partially successful using glutaraldehyde fixed tissue, treated with 302 glycerol, which was frozen-fractured under hexane at -65° C. The tissue was then dehydrated with acetone at ~25° C, critical-point dried and lightly coated with gold. Ultrastructural detail comparable …
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Lanthanide Binding Tag Peptides for Selective Separation of Rare Earth Elements
… of Tb<sup>3+</sup>. Cross-linking with glutaraldehyde enhances foam stability and separation efficiency. (2) Self-assembly of LBT:REE complexes into nanoscale aggregates, characterized by dynamic light scattering, electron microscopy, and anomalous small angle x-ray scattering. Circular …
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