Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Glutamate Signaling"”.
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Spring Forward or Fall Back? Redox State as a Determinant in Glutamate Signaling Pathways Adjusting Our Brain Clock
… Nocturnal light, acting via neurotransmitter glutamate, synchronizes this clock to changes in the external environment by adjusting the phase of the SCN. The phase-resetting response depends on the temporal state of the clock: during the early night, light/glutamate delays clock phase, whereas …
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Gene expression in healing tendon
… of a significant number of genes related to glutamate signaling, a method of cellular communication that has not previously been shown to exist in tendon. Also upregulated were a number of genes which have previously only been associated with embryonic development. Finally, gene expression in …
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The Role of Atypical PKC in the Plasticity of the Circadian Clock in the Rat Suprachiasmatic Nucleus
… transferred by the excitatory neurotransmitter, glutamate (GLU), via the retinohypothalamic tract from the retina to the SCN. Light/GLU pulses can reset the mammalian circadian clock at specific times: in the early night, light/GLU delays clock phase, whereas in the late night, light/GLU advances …
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Neuroprotection from the huntingtin-repressed transcriptional coactivator PGC-1α
… PGC-1α(-/-) mouse causes distinct alterations in glutamatergic signaling that do not mimic the observation of acute knockdown of PGC-1α. We propose that the loss of PGC-1α in a number of neurological disorders contributes to concurrent increases in aberrant glutamate signaling and excitotoxicity …
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Using Multimodal MRI Techniques to Understand the Role of Hippocampus in Schizophrenia
… model for schizophrenia (SZ), reduced glutamate signaling in dentate gyrus could lower the LTP threshold in its target region CA3, thus generates increased associative function in CA3, resulting in memories with psychotic content. The loss of mnemonic functions in dentate gyrus could …
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An emerging role for tcf7l2 at the nexus between metabolic regulation and social behavior
… Several of these pathways connected metabolic signaling to plasticity across the brain in all three model species, indicating the evolutionary importance of these links. One particular pathway called out for deeply conserved mechanistic importance was the WNT pathway, which is known to control …
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Calcium/Calmodulin-Dependent Protein Kinase II Beta (CaMKIIβ): A Regulator of Oligodendrocyte Maturation and Myelination
… axonal protection along with disrupted nerve signaling which can lead to a variety of different debilitating phenotypic responses. It has been shown that there are MS lesions in which oligodendrocyte progenitors are present. However, while these cells are thought to possess the intrinsic …
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Inhibition of cellular glutamate efflux as a novel strategy to curb canine hemangiosarcoma proliferation and survival
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01