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Showing 1 to 15 of 15 for “"Glucose Transporter 1"”.
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Role of glucose transporter 1 during pregnancy
… gene profiling has shown that Hif2α regulates Glucose transporter1 (GLUT1). GLUT1 is the dominant glucose transporter in the uterus and has been linked to human infertility. Based on these points, we chose to investigate the role of GLUT1 in pregnancy by deleting GLUT1 from the uterus using two …
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The effects of herbal extracts and compounds on the glucose metabolism in Hep G2 cells
… secondary metabolites and extracts on glucose metabolism in Hep G2 cellular models. The primary objective of this project is to evaluate and compare the metabolic activities of Hep G2 cells after treatment with pure compounds phloretin, ouabain, berberine, and metformin, rebaudioside-A, …
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HYPOXIA-REGULATED EXPRESSION OF GLUT-1 IN GBM CELL LINES
… 1 (HIF-1). HIF-1 is thought to directly affect glucose transporter 1 (GLUT1) expression levels in hypoxic conditions. This study sought to determine the relationship between HIF-1 and GLUT1 expression levels within normoxic and hypoxic environments utilizing an <em>in-vitro</em> GBM model. The …
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Evaluation of 18F FDG-PET/CT in Patients with Gastric Signet Ring Cell Carcinoma : Correlation with GLUT-1 Expression and Histologic Finding
… investigate the relation between FDG uptake and glucose transporter-1 (GLUT-1) expression in GSRC patients. MATERIALS AND METHODS: Forty patients (28 men, mean age 54±12) with histologically confirmed GSRC who underwent a pre-operative PET/CT were enrolled. The maximum standardized uptake value …
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Different Effect of 5-Fluorouracil on Expression of Genes Related to Aerobic Glycolysis According to Chemoresponsiveness in Gastric Cancer Cells
… genes (GLUT1, PGK1 and PDK1), and the rate of glucose uptake in those cells. HIF 1α was highly expressed in SNU216, and the responsiveness of SNU216 to 5-FU was lower than it of MKN45. The expressions of glucose transporter 1(GLUT1), phospho-glycerate kinase 1(PGK1) and pyruvate …
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Characterization of GSDMD as a Positive Regulator of Breast Cancer Cell Proliferation and Mammary Tumorigenesis
… protein-protein interaction between GSDMD and glucose transporter 1 (GLUT1), a protein pivotal in glucose uptake and metabolism. Here, we revealed that GSDMD and GLUT1’s interaction synergistically enhanced glucose transport activity and cell proliferation in BC cells. Future elucidation of …
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Regulation of glucose transporters in sheep placenta
Transplacental glucose transport is vital to fetal growth. Although the presence of glucose transporter-1 (GLUT1) and GLUT3 has been demonstrated in mammalian placenta, the factors regulating these genes remain unclear. Therefore, the overall aim of these studies was to clone ovine GLUT1 (oGLUT1) …
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Mechanism of mitochondrial respiratory dysfunction by oncogenic K-Ras
… mainly through glycolysis without induction of glucose transporter 1 (GLUT1), which has a low Km value and is a well-known glucose transporter induced by oncogenic Ras signaling. Finally, LC3-II formation, which is indicative of autophagy initiation, was modulated by extracellular glucose levels …
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Suppression of Carcinogenesis and Tumor Progression by an Energy Restriction-Mimetic Agent in Murine Models of Prostate Cancer
… that can induce a response similar to that of glucose restriction in vitro and caloric restriction in vivo are needed. These agents are termed energy-restriction mimetic agents (ERMAs) and include 2-deoxyglucose, resveratrol, and the thiazolidinedione derivatives OSU-CG12 and OSU-CG5. Here, we …
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Mechanisms underlying monosaccharide stimulated incretin hormone secretion from the intestine
… in the pancreas and brain to improve blood glucose and appetite control. Due to the therapeutic benefits of GLP-1 signalling, understanding the factors that regulate its release are of continued interest. Gut hormones are produced by enteroendocrine cells (EECs) of the intestinal epithelium …
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Small molecule kaempferol, a novel regulator of glucose homeostasis in diabetes
… 5 months (mo) improved insulin sensitivity and glucose tolerances, which were associated with increased Glut4 and AMPKα expression in muscle and adipose tissues in middle-aged mice fed a high-fat (HF) diet. In vitro, kaempferol increased lipolysis and restored chronic high fatty acid-impaired …
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IMMUNOMODULATION AND INTESTINAL BARRIER PROTECTION ACTIVITIES OF A NOVEL SYNTHETIC GLUCOSE ANALOGUE IN INFLAMMATORY ANIMAL MODEL OF COLITIS AND ASTHMA.
… for the intake of food and air. SGLT-1 is a co-transporter able to absorb D-glucose, against a concentration gradient, together with Na+. The expression of SGLT-1 on the apical membrane of enterocytes, the cells that line the gut and overlook to the intestinal lumen, is fundamental in order to …
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Developmental Regulation of the Expression of Nutrient Transporter and BrushBorder Membrane Hydrolase Genes in the Small Intestine of Piglets
… regulation of the expression of nutrient transporter and brushborder hydrolase genes in the small intestine of piglets. Seventy piglets from seven sows were killed at birth (d 0), during suckling (d 1, 3, 7, 14, 21) and postweaning (d 22, 24, 28, 35), and intestinal segments (duodenum, …
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Mechanisms underlying uterine function during establishment of pregnancy
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-05-01
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Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy
Embargo set by: Seth Robbins for item 73141 Lift date: 2017-01-21T19:56:18Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system