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Showing 1 to 2 of 2 for “"Glucocorticoid Sensitivity"”.

  1. Modelling altered Glucocorticoid Sensitivity: From HPA axis to metabolic abnormalities in mice and humans

    The primary determinants of tissue glucocorticoid action are glucocorticoid receptor (GR) density and intracellular levels of ligand, the latter determined both by activity of the hypothalamic-pituitary-adrenal (HPA) axis and cellular activity of 11beta- hydroxysteroid dehydrogenase (11beta-HSD) …

    edinburgh Repository record for Modelling altered Glucocorticoid Sensitivity: From HPA axis to metabolic abnormalities in mice and humans (opens in a new tab)

  2. Effects of Psychological Stress on Glucocorticoid Sensitivity of Inflammatory Response to Influenza Vaccine Challenge in Healthy Military College Students

    … suggests that chronic stress impairs immune cell glucocorticoid sensitivity (GCS), leading to excessive production of proinflammatory cytokines. This pathway may contribute to impaired immune responses to vaccination and increased risk of infectious illness in military personnel in high stress …

    ohiolink Repository record for Effects of Psychological Stress on Glucocorticoid Sensitivity of Inflammatory Response to Influenza Vaccine Challenge in Healthy Military College Students (opens in a new tab)