Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Glucagon-like peptide 2"”.
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Short-Chain Fatty Acids and Glucagon -Like Peptide-2 Enhance Intestinal Development and Adaptation
… at minimizing the need for TPN are necessary. Glucagon-like peptide-2 (GLP-2) may be a therapeutic agent as it reduces TPN associated atrophy and increases enzyme and transporter activity. To examine this, we coinfused GLP-2 with TPN and found increased ileal mRNA and protein abundance of the …
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Influences of milk intake and dietary inclusion of a bioactive extract from the olive (Olea europaea) on glucagon-like peptide-2 and its effects on growth and intestinal health of dairy calves
… integrity is associated with an intestinal peptide, glucagon-like peptide-2 (GLP-2), which stimulates proliferation, decreases apoptosis, enhances intestinal barrier function, and decreases intestinal inflammation. During diarrheic episodes and at weaning, feed intake is reduced, potentially …
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Rice bran supplementation modulates environmental enteric dysfunction markers and serum metabolites in weaning Nicaraguan infants
… beneficial effects on gut function in the serum Glucagon-like-peptide-2 (p<0.04). Fifty-four serum metabolites were significantly different following RB supplementations versus control. These results support multiple favorable outcomes from RB supplementation in weaning infants. Findings from …
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Nutrient Transport During Hypoperfusion
… alteration. It is possible that nutrients and peptide hormones can be used to upregulate nutrient transport in the compromised state. The addition of butyrate in vitro and ex vivo caused an increase in SGLT-1 transporter activity. Therefore, a study was performed to test the luminal addition of …
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Butyrate-Induced Expression of Proglucagon: Implications for Enteroendocrine Signaling and Intestinal Growth
… distal ileum and colon which expresses the proglucagon gene. Proglucagon encodes a number of important hormones, namely glucagon-like peptide 1 (GLP-1), glucagon-like peptide 2 (GLP-2), glicentin, and oxyntomodulin and thus may impact intestinal development and dysfunction, type 2 diabetes, and …
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Butyrate-induced expression of proglucagon: implications for enteroendocrine signaling and intestinal growth
… distal ileum and colon which expresses the proglucagon gene. Proglucagon encodes a number of important hormones, namely glucagon-like peptide 1 (GLP-1), glucagon-like peptide 2 (GLP-2), glicentin, and oxyntomodulin and thus may impact intestinal development and dysfunction, type 2 diabetes, and …
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Calf intestinal health: assessment and dietary interventions for its improvement
… from prebiotic overdosing caused the diarrhea like condition observed in these animals. Definition of the galactooligosacharide dose response curves and its dependence on milk feeding rates is crucial to optimize use of this prebiotic in terms of calf health. Lastly, another experiment was …
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Generation and use of new tools for the characterisation of gut hormone receptors
… has been on the receptors of the gut hormones glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-2 (GLP-2). In recent years there has been a surge of interest in the enteroendocrine hormones particularly due to the success of GLP-1 …
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Quantitation of enteroendocrine hormones as metabolic disease biomarkers in human biological matrices by liquid chromatography tandem mass spectrometry
Polypeptides are widely present in biology and many of them act as biomarkers, both for disease and system regulation. Many gut hormone peptides are secreted by enteroendocrine cells (EECs) and some, known as incretins, are released after a meal to control blood glucose and stimulate neuronal …
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Pre-, pro-, and synbiotic modulation of the intestinal microbiota stimulates enteroendocrine mediated intestinal adaptation in piglets with short-bowel syndrome
… cascade beginning with intestinal secretion of glucagon-like peptide-2 (GLP-2), an intestinotrophic hormone, stimulating innate intestinal adaptation. Treatments such as prebiotics and probiotics that increase luminal production of short-chain fatty acids (SCFA), especially butyrate, could …
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The role of the free fatty acid, lauric acid, in appetite regulation and its potential as an appetite-suppressant.
… antropyloroduodenal (APD) region and stimulates glucagon-like peptide-1 (GLP-1) secretion, while both C12 and C10 stimulate cholecystokinin (CCK) secretion, however, the effect of C12 was much greater. A previous study in humans has also shown that intraduodenal administration of a long-chain …
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Butyrate-induced upregulation of intestinal glucose transport and signaling pathways represent a possible nutrient therapy for individuals with malabsorptive disorders
… Dawley rat as an in vivo model. Finally, proglucagon mRNA, and the G-protein coupled receptors (GPCR), Free Fatty Acid Receptor FFAR2) and Free Fatty Acid Receptor 3 (FFAR3), were measured. To establish that butyrate increased the glucose transport capacity of the intestine through …