Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 177 for “"Glu"”.
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Enzymatic Characterization Of The Ammonia Tunnel In Helicobacter Pylori Asp-Trnaasn/glu-Trnagln Amidotransferase
… (<i>H. pylori</i>) Asp-tRNA<sup>Asn</sup>/Glu-tRNA<sup>Gln</sup> amidotransferase (AdT) plays important roles in indirect aminoacylation and translational fidelity; however, its inter-domain communication and ammonia delivery mechanisms are not well understood. In the present study, we …
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MECHANISMS OF NEUROPROTECTION IN SCN2.2 CELLS
As the major excitatory neurotransmitter, glutamate (Glu) is physiologically important in brain function. Excessive Glu release, however, is a critical underlying pathological mechanism in neurodegenerative disease, especially stroke. Strategies to protect neurons from cell death under these …
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The Role of Atypical PKC in the Plasticity of the Circadian Clock in the Rat Suprachiasmatic Nucleus
… transferred by the excitatory neurotransmitter, glutamate (GLU), via the retinohypothalamic tract from the retina to the SCN. Light/GLU pulses can reset the mammalian circadian clock at specific times: in the early night, light/GLU delays clock phase, whereas in the late night, light/GLU advances …
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Development of a HPLC method for the determination of methotrexate (MTX) and MTX-polyglutamates of red blood cells: A dissertation submitted in partial fulfilment of the requirements for the Degree of Bachelor of Science with Honours at Lincoln University
… of MTX and active metabolites, MTX polyglutamates (glu)s in the cells. MTX(glu)s are retained in red blood cells (RBC) and have a half-life of 4 to 6 weeks. Measuring these metabolites is relevant as a steady RBC MTX and MTX(glu) level can be achieved following 6 to 8 weeks continuous …
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Calidad harino-panadera en trigo blando (T. aestivum L.) : influencia de las prolaminas y microsatélites relacionados
… determinar la influencia de las subunidades de gluteninas de alto (HMW) y bajo peso molecular (LMW) y las gliadinas, e identificar marcadores moleculares microsatelites (SSRs) ligados a QTLs de calidad harino-panadera en trigo blando (Triticum aestivum L.) Se utilizaron 79 lineas recombinantes …
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Experimental spectroscopic and theoretical studies of amino acid derivatives
… derivatives, i.e. N-acetyl-L-Asp, N-acetyl-L-Glu, and di-amino acid peptide/derivatives, i.e. L-Asp-L-Glu, a-N-acetyl-L-Asp-L-Glu, and ß-N-acetyl-L-Asp-L-Glu are reported. The calculated structures for N-acetyl-L-Asp and N-acetyl-L-Glu differ. The conformation of the trans amide moiety changes …
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Conducting polymer hydrogels for the release of glutamate and sensing of extracellular action potentials
… delivery device suitable for the delivery of glutamate (Glu) in response to native cellular signalling, namely a CPH for drug delivery, and a CPH for coating microelectrodes. Methods: A stability indicating high performance liquid chromatography (HPLC) method was developed for the …
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Integrated Entrainment of the Suprachiasmatic Clock by the Two Neurotransmitters of the Retinohypothalamic Tract, Glutamate and PACAP
The functional interaction between PACAP and Glu was then investigated. PACAP blocked the phase advance normally induced by Glu at late night, while anti-PACAP reagents augmented the Glu-induced phase advance in the SCN slice as well as the light-induced phase advance in vivo. In the early night, …
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Understanding How Sequence Differences Among Glutamate Transporters Might Contribute to their Differential Function in Glutamate Clearance in C. elegans
… clearance of the neurotransmitter. Glutamate-mediated neurotransmission involves the release of glutamate (Glu) into the synaptic cleft by the presynaptic cell and binding to glutamate receptors (GluR) on the postsynaptic cell, leading to activation of a signal transduction cascade. …
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Angiotensin II modulates glutamate-induced depolarizations and synaptic transmission in rat locus coeruleus neurons in vitro.
… actions of AII on spontaneous activity and on Glu-induced responses in rat locus coerulus neurons. The action of AII appears to be selective since it had no effect on the depolarizations evoked by acetylcholine (ACh), or by depolarizing current injections. Selectivity is also indicated by the …
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Mammalian TIMELESS and Protein Kinase G: Partners Linking the Molecular Clockwork to Environmental Light
Research in our lab has determined that GLU activates Protein Kinase G (PKG), and that this activation is required for the mammalian GLU-induced phase advance. Since the Drosophila phase advance proceeds through phosphorylation-dependent degradation of Drosophila TIMELESS (dTIM), I hypothesized …
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Untersuchungen zur Zusammensetzung, Stabilität und Struktur von Cadmiumkomplexen mit biologisch und medizinisch relevanten Liganden
… die Komplexbildungskonstanten von Cd(II) mit Glutathion (gamma-Glu-Cys-Gly), Phytochelatin 2 (gamma-Glu-Cys-gamma-Glu-Cys-Gly) und meso-2,3-Dimercaptobernsteinsäure, sowie die Protonierungskonstanten dieser Liganden bestimmt. Die experimentelle Vorgehensweise, wie auch die Auswertung mit dem …
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Effects of Small Intestinal Starch Digestion and Dietary Lipid on Efficiency of Nitrogen Use in Cattle
… 0, 30.9 ± 0.59, 62.4 ± 1.16, or 120.4 ± 3.39 g/d Glu, or 387.9 ± 17.47 g/d casein. Casein increased (P = 0.05) SISD. Similarly, greater duodenal Glu linearly (P = 0.02) increased SISD. Starch flow to the ileum decreased (<em>Linear</em> = 0.04) in response to greater postruminal Glu. Ileal flow of …
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Prolaminas y marcadores moleculares relacionados con la calidad en Trigo Duro (Triticum turgidum L.)
… alelica de un tipo de prolaminas denominadas gluteninas de bajo peso molecular (LMW-GS) pero estas no explican todas las diferencias encontradas en la calidad. Por ello, hemos localizado e identificado otro tipo de marcadores que expliquen esa variacion que las prolaminas no llegan a explicar. …
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Evaluation of Glutamatergic Treatment in Reducing Nicotine Seeking Behavior in Rats
… Recent studies have highlighted changes in glutamate (GLU) homeostasis in the circuitry from the prefrontal cortex (PFC) to the nucleus accumbens (Nacc) as vital in the reinstatement of drug-seeking behavior. Restoring basal concentrations of extracellular GLU, thereby increasing tonic …
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Níveis de ácido L-glutâmico e de vitamina K no desempenho e deformidades ósseas e perfil de enzimas digestivas de pintos de corte alimentados com dietas purificadas
… inteiramente casualizado 2 x 4 ( 2 níveis de L-glutâmico x 4 níveis de vitamina K), consistindo de 8 tratamentos, 4 repetições de 8 aves cada. Os tratamentos consistiram de uma dieta básica purificada contendo todos os L- aminoácidos indispensáveis, minerais e vitaminas (exceto a Vit. K) …
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Formation of 4(5)-methylimidazole in processed meat and in glucose amino acid model system
… of 94.76 to 103.94%. Formation of 4-MeI in glucose-amino acid model system was studied. [subscript]D-Glucose (Glu) was mixed individually in equimolar concentrations of 0.05, 0.1, or 0.15 M and equal volume with [subscript]L-Alanine (Ala), [subscript]L-Arginine (Arg), Glycine (Gly), …
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Maize Transformation for Resistance to Aspergillus Flavus
The chitinase18 (ch18) and beta-1,3-glucanaseII (glu) genes driven by globulin1 were delivered into H99 and Pa91 type I calli by particle bombardment. Sixteen different transformation events were obtained from H99 calli. Some were crossed with Pa91 the untransformed control and then self-pollinated …
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The Role of The Plasminogen-Fibrin Interaction in The Regulation of Fibrinolysis
… relevance of such a mechanism, the binding of Glu-plasminogen and Lys-plasminogen to fibrin, to immobilized lysine and to plasmin-cleaved fibrin were quantitatively characterized. The effects of two forms of fibrin on the activation kinetics of Glu- and Lys-plasminogen were also studied. The …
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Precursor phases in non-classical crystallization
… with a quaternary model system, containing DL-Glutamic acid (Glu), polyethyleneimine (PEI), water, and EtOH, for the understanding of multistep precipitation of Glu with PEI as an additive. The experiments were performed by mixing Glu-PEI aqueous solution with a non-solvent EtOH. First, the …
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