Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"Glomerulus"”.
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The Role of Von Hippel-Lindau Protein in the Glomerulus
Rapidly progressive glomerulonephritis (RPGN) is a clinical syndrome characterized by loss of renal function within days to weeks and by glomerular crescents on biopsy. The pathogenesis of this disease is unclear, but circulating factors such as antineutrophil cytoplasmic antibodies (ANCA) are …
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Pengaruh pemberian ekstrak jahe merah (Zingiber officinale rosc.) terhadap sel nekrosis pada jaringan glomerulus dan tubulus ginjal tikus putih (Rattus norvegicus) yang terpapar allethrin
… jahe terhadap jumlah sel nekrosis pada jaringan glomerulus dan tubulus ginjal tikus putih. Perlakuan pemberian dosis jahe 200 mg/kg BB efektif untuk menurunkan jumlah sel nekrosis pada jaringan glomerulus dan tubulus dibandingkan dengan dosis 100,125,150,175 mg/kg BB. ENGLISH: Ginger (Zingiber …
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Pengaruh pemberian infusa daun murbei (Morus alba L.) terhadap gambaran histologi gromerulus dan tubulus proksimal tikus putih (Rattus norvegicus) diabetes mellitus kronik
… bebas ini dapat merusak struktur ginjal terutama glomerulus dan tubulus proksimal. Untuk itu diperlukan asupan antioksidan alami yang berasal dari tanaman yaitu daun murbei. Daun murbei banyak mengandung zat aktif antara lain ecdysterone, asam klorogenik dan deoxynojirimycins yang berfungsi untuk …
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Bilateral processing of thermoreception in the olfactory system of larval Xenopus laevis
… einen temperatursensitiven olfaktorischen Glomerulus. Dieser temperatursensitive olfaktorische Glomerulus wird von Axonen olfaktorischer Rezeptorneurone innerviert, die sowohl im ipsilateralen als auch im contralateralen olfaktorischen Epithel liegen. Die Perfusion des ipsilateralen oder …
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Die Wirkung von Agrin auf die Genexpression isolierter Maus-Podozyten in Langzeitkultur
… Arbeit befasst sich mit der Rolle von Agrin am Glomerulus. Am Glomerulus wird das Heparansulfat-Proteoglykan Agrin von Podozyten synthetisiert und daraufhin in die glomeruläre Basalmembran integriert. Als Strukturprotein hilft es, die Podozyten über a-Dystroglycan in der glomerulären …
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Adaptive fabrication of biofunctional decellularized extracellular matrix niche towards complex engineered tissues
… device was constructed. Co-culture of human glomerulus endothelial cells and podocytes was performed on this device, to simulate the blood-to-urine interface in vitro. Good cell attachment and viability were demonstrated, and specific cell differentiation and fibronectin secretion were …
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The Role of Drosophila Odorant Receptors in Odor Coding
… one odorant and one gustatory receptor. One glomerulus receives co-convergent input from two separate populations of olfactory neurons. Three ORs label sexually dimorphic glomeruli implicated in sexual courtship, and are thus candidate Drosophila pheromone receptors. The organization of …
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SREBP-1 and Cell Surface GRP78 are important modulators of TGF-β1 in the progression of diabetic nephropathy
… during the pathogenesis of diabetes occur in the glomerulus. The mesangial cells are a subpopulation of cells in the glomerulus that are responsible for coordinating responses with other nearby cell types. Transforming growth factor (TGF)-β1 is a cytokine that mesangial cells secrete, and has been …
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Concentration-dependent recruitment of mammalian odorant receptors
… provide evidence that ACT activates the Olfr923 glomerulus in the olfactory bulb. This study sheds light on the active process in which unique OR repertoires may collectively facilitate the discrimination of odorant concentrations. Together, these odorant receptors may shape the dynamic aspects …
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Single nephron structure and function, and renal effects of catecholamines in the dogfish, Scyliorhinus canicula
… microscopy. 2. Visceral epithelium of the glomerulus was composed of podocytes, primary processes and interdigitating pedicels. Morphological variations were common, with areas of flattening and broadening of these structures. 3. The nephron was found to be composed of Bowman's capsule, …
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Analysis of the Molecular Mechanisms of Drosophila Antennal Lobe Development
… same odorant receptor converge on one specific glomerulus in the antennal lobe or olfactory bulb, where they synapse with the dendrites of the postsynaptic cells, projection neurons (PNs) or mitral cells. Mutation in derailed/drl gene, a receptor tyrosine kinase, leads to the disruption of the …
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Representations and Transformations of Odor Information in the Mouse Olfactory System
… mitral and tufted cell projections from a given glomerulus to piriform are segregated or distributed, or whether they are random or determined. Distinguishing between these possibilities is important for understanding the function of piriform cortex: a random representation of odor identity in …
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Podocyte Melanocortin 1 Receptor Mediated Signaling
… ACTH treatment are mediated through cells in the glomerulus. Thus, the melanocortin 1 receptor (MC1R) was found to be colocalizing with the podocyte marker synaptopodin. Treatment with MC1R specific agonists had beneficial effects in an experimental model of membranous nephropathy, Passive Heymann …
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Processing of plant-associated odors by a subset of projection neurons in the antennal lobe of the female moth, Manduca sexta
… possibly consists of one uniquely identifiable glomerulus. Furthermore, the results indicate response specificity and a narrow receptive range of certain AC neurons in response to flowers of Solanaceous hostplants. Among the odors tested were nitrogen (N)-bearing compounds, monoterpenes, …
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A Non-Canonical Function for NLRP3 and AIM2 in Kidney Diseases
… AIM2 was detected primarily in podocytes in the glomerulus and distal tubules at a low level. In a mouse model of nephrotoxic serum (NTS)-mediated anti-GBM, Aim2-/- mice displayed increased glomerular cellular crescent (multilayered accumulation of activated parietal cells) formation, tubular …
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Advanced in vivo imaging of the interactions between vascular and renal development in the zebrafish pronephric kidney
… our time-lapse observations to maturation of the glomerulus, and the evolution of perm-selective function. Finally, we explored methods of mechanically obstructing blood-flow in order to investigate whether altered hemodynamic forces would influence pronephric development. We found that in those …
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Critical Period for Murine Olfactory Map Formation
… able to form converging projection into single glomerulus <i>de novo</i>. They also possessed the ability to correct mis-targeted axons. The late born neurons relied on existing axon tracks to target the correct glomeruli. Through genetic chronicle tracing experiments, I was able to demonstrate …
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Modulation of TGFβ-Induced PAI -1 Expression by Changes in Actin Polymerization in Human Mesangial Cells
… deposition of extracellular matrix (ECM) in the glomerulus (glomerulosclerosis). Glomerulosclerosis is associated with activation of normally quiescent glomerular mesangial cells into myofibroblast-like cells. The overall objective of this study is to delineate cellular mechanism/s of …
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Characterisation of the Apelin Receptor and its Endogenous Ligands, Apelin and Elabela/Toddler in the Cardio-Renal System
… ELA and apelin receptor were expressed from glomerulus to the collecting duct of the renal nephron with robust localisation of the receptor to juxtaglomerular apparatus involved in systemic blood pressure regulation. Importantly, in models of kidney disease, the expression of both ligands …
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Regulation of Fluid-phase Uptake in Podocytes by Albumin-associated Lipids
… are specialized epithelial cells in the kidney glomerulus that play important structural and functional roles in maintaining the filtration barrier. In nephrotic syndrome, a major breakdown of the kidney filtration barrier associated with proteinuria, hyperlipidemia, and edema, podocytes undergo …
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